Researchers at UC San Diego and Arizona State University have received $1.7 million in funding from The Michael J. Fox Foundation for Parkinson’s Research to launch a multi-year effort to identify blood-based biomarkers of Parkinson’s disease, which could improve care and accelerate new treatments.
In a study published January 17, 2019 in Translational Psychiatry, researchers at University of California San Diego School of Medicine describe how, in a novel mouse model, epigenetic regulation negatively impacts a downstream gene specifically involved in neurodevelopment and associated behaviors.
Using induced pluripotent stem cell-derived neurons from Alzheimer’s patients, UC San Diego researchers say cholesteryl esters — the storage product for excess cholesterol within cells — act as regulators of the protein tau, providing a new druggable target for the disease.
Researchers at University of California San Diego School of Medicine report that autopsies of patients diagnosed with Alzheimer’s disease when they were alive — and confirmed by autopsy — indicate many cognitive issues symptomatic of the condition are less noticeable in living Hispanic patients.
Researchers at University of California San Diego School of Medicine found that a diet low in free sugars (those added to foods and beverages and occurring naturally in fruit juices) resulted in significant improvement in nonalcoholic fatty liver disease (NAFLD) in adolescent boys.
Early adult general cognitive ability is a stronger predictor of cognitive function and reserve later in life than other factors, such as higher education, occupational complexity or engaging in late-life intellectual activities.
The New York Times, April 23
The San Diego Union-Tribune, April 25
La Jolla Light, April 23
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