Curing the Bystander Effect: A New Base Editing Tool Minimizes Unwanted Edits to DNA
Base editing is still a new technology. Alexis Komor is working to improve its efficiency, while lowering unwanted bystander edits. This occurs when a base editor not only edits the desired nucleobase, but edits surrounding bases as well. Komor’s lab has developed a way to minimize bystander edits.