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News Archive - School of Medicine

Single Injection Alleviates Chemotherapy Pain for Months in Mice

May 29, 2018

UC San Diego School of Medicine researchers found that treating mice with a single spinal injection of a protein called AIBP — and thus switching “off” TLR4, a pro-inflammatory molecule — prevented and reversed inflammation and cellular events associated with pain processing. As reported May 29 by Cell Reports, the treatment alleviated chemotherapy pain in mice for two months with no side effects.

Hot Cars Can Hit Life-Threatening Levels in Approximately One Hour

May 24, 2018

Researchers from University of California San Diego School of Medicine and Arizona State University found that if a car is parked in the sun on a summer day, the interior temperature can reach 116 degrees F. and the dashboard may exceed 165 degrees F. in approximately one hour — the time it can take for a young child trapped in a car to suffer fatal injuries.

In a Break with Dogma, Myelin Boosts Neuron Growth in Spinal Cord Injuries

May 23, 2018

In a new paper, published in the May 23 online issue of Science Translational Medicine, researchers at University of California San Diego School of Medicine report that adult rat myelin actually stimulated axonal outgrowth in rat neural precursor cells (NPCs) and human induced pluripotent (iPSC)-derived neural stem cells (NSCs).

Researchers Operate Lab-Grown Heart Cells by Remote Control

May 18, 2018

Researchers at University of California San Diego School of Medicine and their collaborators have developed a technique that allows them to speed up or slow down human heart cells growing in a dish on command — simply by shining a light on them and varying its intensity. The cells are grown on a material called graphene, which converts light into electricity, providing a more realistic environment than standard plastic or glass laboratory dishes.

Researchers Identify Gene That Helps Prevent Brain Disease

May 16, 2018

A UC San Diego-led team has identified a gene that helps prevent the harmful buildup of proteins that can lead to neurological disorders such as Alzheimer’s and Parkinson’s disease. As published in Nature, the researchers found that the “Ankrd16” gene acts like a failsafe in proofreading and correcting errors to avoid the abnormal production of improper proteins.

California’s First Accredited Geriatric Emergency Department Arrives in La Jolla

May 16, 2018

The Gary and Mary West Emergency Department at UC San Diego Health in La Jolla has been accredited as a geriatric emergency department by the American College of Emergency Physicians (ACEP). The accreditation is the first of its kind and is part of an effort to improve the quality and standards of emergency care provided to the nation’s older patients.

Joint Resolution: A Link Between Huntington’s Disease and Rheumatoid Arthritis

May 15, 2018

Using new analytic tools, researchers at University of California San Diego School of Medicine and the Icahn School of Medicine at Mount Sinai have decoded the epigenetic landscape for rheumatoid arthritis (RA), a common autoimmune disease that affects more than 1.3 million Americans.

Reprogrammed Stem Cell-Derived Neurons Survive Long-Term in Pigs with Spinal Cord Injuries

May 9, 2018

In a new paper, an international team led by scientists at University of California San Diego School of Medicine describe successfully grafting induced pluripotent stem cell (iPSC)-derived neural precursor cells back into the spinal cords of genetically identical adult pigs with no immunosuppression efforts. The grafted cells survived long-term, displayed differentiated functionality and caused no tumors.

California Researchers Call for Volunteers as NIH’s Landmark Precision Medicine Study Launches

May 1, 2018

The All of Us Research Program officially opens for enrollment Sunday, May 6. Led by the National Institutes of Health (NIH), All of Us is an unprecedented effort to gather genetic, biological, environmental, health and lifestyle data from 1 million or more volunteer participants living in the United States. A major component of the federal Precision Medicine Initiative, the program’s ultimate goal is to accelerate research and improve health.

Surgeons Preserve Patients’ Hearing with Innovative Brainstem Implant

April 30, 2018

Patients with rare brain tumors on the auditory nerve now have an option to prevent complete deafness at UC San Diego Health. The device, called an auditory brainstem implant or ABI, fits behind the ear and connects directly to the brainstem. The device enables patients with neurofibromatosis type 2 (NF2) who develop bilateral hearing nerve tumors to be aware of environmental sounds, such as a door opening, a phone ringing or a car approaching.
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