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News Archive - School of Medicine

Medtech Meets Cleantech: Malaria Vaccine Candidate Produced from Algae

February 18, 2015

Researchers at University of California, San Diego School of Medicine used algae as a mini-factory to produce a malaria parasite protein. The algae-produced protein, paired with an immune-boosting cocktail suitable for use in humans, generated antibodies in mice that nearly eliminated mosquito infection by the malaria parasite. The method is the newest attempt to develop a vaccine that prevents transmission of the malaria parasite from host to mosquito.

Autism Genes Activate During Fetal Brain Development

February 18, 2015

Scientists at the University of California, San Diego School of Medicine have found that mutations that cause autism in children are connected to a pathway that regulates brain development.

New Insights into 3D Genome Organization and Genetic Variability

February 18, 2015

While genomics is the study of all of the genes in a cell or organism, epigenomics is the study of all the genomic add-ons and changes that influence gene expression but aren’t encoded in the DNA sequence. A variety of new epigenomic information is now available in a collection of studies published Feb. 19 in Nature by the National Institutes of Health (NIH) Roadmap Epigenomics Program.

Tau-Associated MAPT Gene Increases Risk for Alzheimer’s Disease

February 17, 2015

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, has identified the microtubule-associated protein tau (MAPT) gene as increasing the risk for developing Alzheimer’s disease (AD). The MAPT gene encodes the tau protein, which is involved with a number of neurodegenerative disorders, including Parkinson’s disease (PD) and AD. These findings provide novel insight into Alzheimer’s neurodegeneration, possibly opening the door for improved clinical diagnosis and treatment.

Early Retina Cell Changes in Glaucoma Identified

February 11, 2015

To better understand these cellular changes and how they influence the progression and severity of glaucoma, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute turned to a mouse model of the disease. Their study, published Feb. 10 in The Journal of Neuroscience, reveals how some types of retinal ganglion cells alter their structures within seven days of elevated eye pressure, while others do not.

Newly Named Shiley Eye Institute Projects Bigger, Bolder Vision

February 11, 2015

Reflecting its emergence as a regional hub for unparalleled clinical care, research, education and community service, the UC San Diego Shiley Eye Center has been renamed the UC San Diego Donald P. and Darlene V. Shiley Eye Institute, encompassing the Shiley Eye Center, the Anne F. and Abraham Ratner Children’s Eye Center, the Hamilton Glaucoma Center and the Joan and Irwin Jacobs Retina Center.

Building Mini-Brains to Study Disorders Caused by HIV and Meth Use

February 10, 2015

A University of California, San Diego School of Medicine project involving the creation of miniature models of the human brain – developed with stem cells – to study neurological disorders caused by HIV and methamphetamine use has been named one of five recipients of the 2015 Avant-Garde Award for HIV/AIDS Research from the National Institute on Drug Abuse (NIDA).

National Grant Funds Project to Address Safety and Wellbeing of Older Drivers

February 9, 2015

Researchers at the UC San Diego School of Medicine will share a $12 million grant with peer institutions across the United States to better understand the factors that influence the safety of older drivers, such as physical and cognitive functions, medical conditions, medications and adoption of vehicle technologies.

MRI Technique Developed for Nonalcoholic Fatty Liver Disease in Children

February 5, 2015

Between 5 and 8 million children in the United States have nonalcoholic fatty liver disease (NAFLD), yet most cases go undiagnosed. To help address this issue, researchers at UC San Diego School of Medicine have developed a new magnetic resonance imaging (MRI)-based technique to help clinicians and researchers better detect and evaluate NAFLD in children.

Researchers Identify Key Mechanisms Underlying HIV-Associated Cognitive Disorders

February 3, 2015

New findings by researchers at the University of California, San Diego School of Medicine open the door to the development of new therapies to block or decrease cognitive decline due to HIV-associated neurocognitive disorders (HAND), estimated to affect 10 to 50 percent of aging HIV sufferers to some degree.
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