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News Archive - School of Medicine

New Biomarker Identifies Colon Cancer Patients Who May Benefit from Chemotherapy

January 20, 2016

Using a new computer science approach, researchers at University of California, San Diego School of Medicine, Columbia University and Stanford University discovered a distinctive molecular feature — a biomarker — that identified colon cancer patients who were most likely to remain disease-free up to five years after surgery. The biomarker, a protein called CDX2, also helped the researchers identify Stage II colon cancer patients who are most likely to benefit from chemotherapy after surgery.

GenomeSpace “Recipes” Help Biologists Interpret Genomic Data

January 20, 2016

Researchers at University of California, San Diego School of Medicine and collaborators developed GenomeSpace, a cloud-based, biologist-friendly platform that connects more than 20 bioinformatics software packages and resources for genomic data analysis. The team is now developing and crowdsourcing “recipes” — step-by-step workflows — to better enable non-programming researchers to interpret their genomic data. The work is described in a paper published January 18, 2016 in Nature Methods.

UC San Diego and Samsara Sciences Team Up to Advance Liver Tissue Models

January 14, 2016

Researchers at University of California, San Diego School of Medicine and Samsara Sciences, Inc., a wholly-owned subsidiary of Organovo Holdings, Inc., have entered into an agreement focused on the development of techniques and methods for the isolation and characterization of liver cells that will help drive new research on liver biology, drug safety and efficacy, and the treatment of liver diseases.

Noted Canadian Neurologist to Head UC San Diego Alzheimer’s Disease Cooperative Study

January 14, 2016

Howard Feldman, MD, FRCP(C), a renowned Canadian neurologist noted for his original research in geriatric cognitive disorders and expertise in large-scale clinical trials, has been named the new director of the Alzheimer’s Disease Cooperative Study (ADCS) at University of California, San Diego, pending approval from the National Institute on Aging (NIA).

Neurosurgeons Evaluate Precision Laser Treatment Of Brain Tumors at UC San Diego Health

January 13, 2016

Neurosurgeons at UC San Diego Health have initiated a landmark, multi-center study to evaluate how the treatment of brain tumors using the NeuroBlate system, a minimally invasive, FDA-approved laser device, impacts the quality of life of patients.

Vaccine Targets Alzheimer’s Disease-like Characteristics in People with Down Syndrome

January 13, 2016

In the first clinical trial of its type, researchers at University of California, San Diego School of Medicine and the Alzheimer’s Disease Cooperative Study (ADCS), in collaboration with AC Immune, a biotechnology company based in Switzerland, will test the safety and tolerability of an immunotherapy vaccine that targets Alzheimer’s disease-like characteristics in adults with Down syndrome.

First Human In Vitro Model of Rare Neurodegenerative Condition Created

January 13, 2016

Researchers at University of California, San Diego School of Medicine and Rady Children’s Hospital-San Diego have created the first stem cell-derived in vitro cellular model of a rare, but devastating, neurodegenerative condition called Cockayne syndrome (CS).

UC San Diego Skaggs School of Pharmacy and Janssen R&D Collaborate to Treat Chagas Disease

January 7, 2016

Researchers at the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego have entered into a research collaboration with Janssen Research & Development, LLC (Janssen R&D), one of the Janssen Pharmaceutical Companies of Johnson & Johnson, to identify new therapeutic targets for Chagas disease, a parasitic infection that is the leading cause of heart failure in Latin America.

UC San Diego Researchers Link Higher Risk of Leukemia to Low Sunlight and Vitamin D

January 6, 2016

Epidemiologists at University of California, San Diego School of Medicine report that persons residing at higher latitudes, with lower sunlight/ultraviolet B (UVB) exposure and greater prevalence of vitamin D deficiency, are at least two times at greater risk of developing leukemia than equatorial populations.

Medical Research Influenced by Training ‘Genealogy’

January 4, 2016

By analyzing peer-reviewed scientific papers that examined the effectiveness of a surgical procedure, researchers at University of California, San Diego School of Medicine provide evidence suggesting that the conclusions of these studies appear to be influenced by the authors’ mentors and medical training.
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