February 22, 2016
February 22, 2016 —
Researchers at University of California, San Diego School of Medicine have discovered that HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. The study, published February 22, 2016 in Nature Microbiology, identifies a new mechanism for controlling HIV replication and its interaction with the host immune system.
February 18, 2016
February 18, 2016 —
As men age, their testosterone levels decrease, but prior studies of the effects of administering supplements of the hormone to older men have been inconclusive. Now, researchers at University of California, San Diego School of Medicine and 12 other medical centers in the United States have shown that testosterone treatment for men over the age of 65 improves sexual function, walking ability and mood.
February 18, 2016
February 18, 2016 —
An international team of scientists, led by researchers at University of California, San Diego School of Medicine and the J. Craig Venter Institute (JCVI), have created the first comprehensive, cross-species genomic comparison of all 20 known species of Leptospira, a bacterial genus that can cause disease and death in livestock and other domesticated mammals, wildlife and humans.
February 17, 2016
February 17, 2016 —
As a public research university, UC San Diego is committed to the highest standards of integrity in research.
February 11, 2016
February 11, 2016 —
A single human gene can produce many different proteins. In the first large-scale study of its kind, researchers at University of California, San Diego School of Medicine, Dana-Farber Cancer Institute and McGill University report that most of these sibling proteins encoded by the same gene — known as protein isoforms — often play radically different roles within tissues and cells.
February 10, 2016
February 10, 2016 —
Alcohol itself can directly damage liver cells. Now researchers at University of California, San Diego School of Medicine report evidence that alcohol is also harmful to the liver for a second reason — it allows gut bacteria to migrate to the liver, promoting alcohol-induced liver disease. The study, conducted in mice and in laboratory samples, is published February 10 in Cell Host & Microbe.
February 8, 2016
February 8, 2016 —
A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver’s sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling. Researchers said the advance could help pharmaceutical companies save time and money when developing new drugs.
February 8, 2016
February 8, 2016 —
Roughly one-quarter of all Americans – an estimated 100 million adults and children – have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure. Combining a diverse array of basic science, biomarkers, imaging and clinical efforts, University of California, San Diego School of Medicine has launched a new NAFLD Research Center to better understand the disease and develop treatments where none currently exist.
February 1, 2016
February 1, 2016 —
Twenty-two University of California, San Diego scientists and physicians are among the 2015 listing of “The World’s Most Influential Scientific Minds,” an annual compendium of “Highly Cited Researchers” by Thomson Reuters, a multinational mass media and information company.
February 1, 2016
February 1, 2016 —
In a small pilot study, researchers at University of California, San Diego School of Medicine and Icahn School of Medicine at Mount Sinai determined that a simple swab to transfer vaginal microbes from a mother to her C-section-delivered newborn can alter the baby's microbial makeup (microbiome) in a way that more closely resembles the microbiome of a vaginally delivered baby.
