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News Archive - Biological Sciences

Tiny Parasite May Contribute to Declines in Honey Bee Colonies by Infecting Larvae

May 27, 2015

Biologists at UC San Diego have discovered that a tiny single-celled parasite may have a greater-than expected impact on honey bee colonies, which have been undergoing mysterious declines worldwide for the past decade.

More Anti-inflammatory Genes Mean Longer Lifespans for Mammals

April 7, 2015

We age in part thanks to “friendly fire” from the immune system — inflammation and chemically active molecules called reactive oxygen species that help fight infection, but also wreak molecular havoc, contributing to frailty, disability and disease. The CD33rSiglec family of proteins are known to help protect our cells from becoming inflammatory collateral damage, prompting researchers at the University of California, San Diego School of Medicine to ask whether CD33rSiglecs might help mammals live longer, too.

New Genetic Method Promises to Advance Gene Research and Control Insect Pests

March 19, 2015

Biologists at the University of California, San Diego have developed a new method for generating mutations in both copies of a gene in a single generation that could rapidly accelerate genetic research on diverse species and provide scientists with a powerful new tool to control insect borne diseases such as malaria as well as animal and plant pests.

Medtech Meets Cleantech: Malaria Vaccine Candidate Produced from Algae

February 18, 2015

Researchers at University of California, San Diego School of Medicine used algae as a mini-factory to produce a malaria parasite protein. The algae-produced protein, paired with an immune-boosting cocktail suitable for use in humans, generated antibodies in mice that nearly eliminated mosquito infection by the malaria parasite. The method is the newest attempt to develop a vaccine that prevents transmission of the malaria parasite from host to mosquito.

Study Sheds Light on What Causes Cells to Divide

December 24, 2014

When a rapidly-growing cell divides into two smaller cells, what triggers the split? Is it the size the growing cell eventually reaches? Or is the real trigger the time period over which the cell keeps growing ever larger? A novel study published online today in the journal Current Biology has finally provided an answer to this long unsolved conundrum. And it’s not what many biologists expected.

Cells Can Use Dynamic Patterns to Pluck Signals From Noise

December 11, 2014

Scientists have discovered a general principle for how cells could accurately transmit chemical signals despite high levels of noise in the system, they report in Science this week.

The Dirty Side of Soap

November 17, 2014

Triclosan is an antimicrobial commonly found in soaps, shampoos, toothpastes and many other household items. Despite its widespread use, researchers at University of California, San Diego School of Medicine report potentially serious consequences of long-term exposure to the chemical.

Moderate Levels of ‘Free Radicals’ Found Beneficial to Healing Wounds

October 13, 2014

Long assumed to be destructive to tissues and cells, “free radicals” generated by the cell’s mitochondria—the energy producing structures in the cell—are actually beneficial to healing wounds. That’s the conclusion of biologists at UC San Diego who discovered that “reactive oxygen species”—chemically reactive molecules containing oxygen, such as peroxides, commonly referred to as free radicals—are necessary for the proper healing of skin wounds in the laboratory roundworm C. elegans.

New Genetic ‘Operating System’ Facilitated Evolution of ‘Bilateral’ Animals

September 30, 2014

The evolution of worms, insects, vertebrates and other “bilateral” animals—those with distinct left and right sides—from less complex creatures like jellyfish and sea anemones with “radial” symmetry may have been facilitated by the emergence of a completely new "operating system" for controlling genetic instructions in the cell.

Four UC San Diego Teams Win NIH Grants from Obama’s BRAIN Initiative

September 30, 2014

Four teams of scientists at UC San Diego will receive research grants from the National Institutes of Health that will help lay the groundwork for visualizing the circuits of the brain and how they work, the agency announced at a White House ceremony today.
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