July 9, 2018
July 9, 2018 —
Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 (DYRK2) at the atomic level. This previously unreported biochemical interaction of curcumin leads to inhibition of DYRK2 that impairs cell proliferation and reduces cancer burden.
April 19, 2018
April 19, 2018 —
For Angela Valdez, being diagnosed with diabetes was an awakening. The disorder ran in her family, but she didn't think it would happen to her. And when it did, she acted by modifying her diet and physical activity. She was doing everything right - almost.
March 26, 2018
March 26, 2018 —
Receptivity to advertising for e-cigarettes, cigarettes and cigars were confirmed to be associated with those who would try the respective tobacco product within one year. However, receptivity to e-cigarette advertising also independently increased the odds that 12- to 21-year-olds who have never smoked would try cigarette smoking within the next year by 60 percent. This finding, publishing in the March 26 issue of JAMA Pediatrics, was independent of receptivity to cigarette advertising.
February 28, 2018
February 28, 2018 —
Science continues to peel away layers of the skin microbiome to reveal its protective properties. In a study published in Science Advances on February 28, University of California San Diego School of Medicine researchers report a potential new role for some bacteria on the skin: protecting against cancer.
February 8, 2018
February 8, 2018 —
Ever wonder why obese bodies burn less calories or why dieting often leads to a plateau in weight loss? In both cases the body is trying to defend its weight by regulating energy expenditure. In a paper publishing in Cell on February 8, University of California San Diego School of Medicine researchers identify the enzyme TANK-binding kinase 1 (TBK1) as a key player in the control of energy expenditure during both obesity and fasting.
February 7, 2018
February 7, 2018 —
Treating obese mice with catestatin (CST), a peptide naturally occurring in the body, showed significant improvement in glucose and insulin tolerance and reduced body weight, report University of California San Diego School of Medicine researchers.
January 11, 2018
January 11, 2018 —
UC San Diego Health and Eisenhower Health signed a five-year affiliation agreement to expand cancer services for residents of Coachella Valley. Starting in January 2018, as a member of the UC San Diego Health Cancer Network, patients of Eisenhower Health will have enhanced access to world-class cancer care, both at Eisenhower Lucy Curci Cancer Center and at UC San Diego Health.
December 20, 2017
December 20, 2017 —
Pharmaceutical interventions are routinely prescribed to help people quit smoking. However, a new study by University of California San Diego School of Medicine researchers suggests that, despite promising results in clinical trials, smoking cessation drugs alone may not be improving the chances of successful quitting among smokers in general.
December 18, 2017
December 18, 2017 —
An online survey of 900 consumers of three of the United States’ most popular cigarette brands suggests that adopting standardized cigarette packing may reduce consumers’ misconceptions that some cigarettes are less harmful than others, reports a team of researchers led by University of California San Diego School of Medicine and published in BMJ Tobacco Control.
December 11, 2017
December 11, 2017 —
Rare stem-like tumor cells play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, report University of California San Diego School of Medicine and Moores Cancer Center researchers.
