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News Archive - Mario Aguilera

Hungry for Love: Gut Molecule Discovered that Flips the Feeding-to-Mating Switch

February 9, 2022

Scientists have identified a molecule released from the fruit fly gut after a protein-rich meal that switches their focus from eating to courtship. The discovery of Dh31, a type of chemical messenger, opens the door to unexplored areas of gut-to-brain communication.

A Map for the Sense of Smell

January 28, 2022

Our sensory systems provide us with immediate information about the world around us. Researchers have created the first sensory map for smell. The map details how the fruit fly’s olfactory receptor neurons, the components that sense smell, are organized within the insect’s sensory hairs.

New Tool Assesses Evolutionary Risks of Antibiotics

January 18, 2022

Countering a rising antibiotic resistance crisis, doctors now prescribe combinations of antibiotics. Yet many risks are involved with such multi-drug combinations. Scientists have developed a way to help doctors evaluate outcomes for different drug pairs and boost the odds of successful treatment.

Genetic Strategy Reverses Insecticide Resistance

January 14, 2022

Using CRISPR/Cas9 technology, scientists have genetically engineered a method to reverse insecticide resistance. The gene replacement method offers a new way to fight deadly malaria spread and reduce the use of pesticides that protect valuable food crops.

Biologists Pinpoint Key Factor in Immune System Response to Viral Infection

January 13, 2022

Researchers studying how small worms defend themselves against pathogens have discovered a gene that acts as a first-line response against infection. They identified “ZIP-1” as a centralized hub for immune response, a finding could have implications for understanding human immunity against viruses.

Scientists Expand CRISPR-Cas9 Genetic Inheritance Control in Mammals

January 11, 2022

UC San Diego biologists have developed a method for genetic inheritance control in male mice, an achievement that advances new laboratory models in an array of research pursuits, from investigations of human disease to therapeutic drug design to invasive species removal.

‘Simple’ Bacteria Found to Organize in Elaborate Patterns

January 6, 2022

Researchers have discovered that communities of bacteria are far more advanced than previously believed. Scientists found that cells within these communities are organized in elaborate patterns, a feature previously associated with higher-level organisms such as plants and animals.

Neurobiologists Reveal How Value Decisions are Coded into Our Brains

November 23, 2021

A new study is showing how value choices are recorded in our brains. Researchers found that persistency allows value signals to be most effectively represented, or “coded,” across different areas of the brain, especially in a critical area within the cerebrum known as the retrosplenial cortex.

New Research Helps Explain the Genetic Basis of Why We Look the Way We Do

November 10, 2021

Comparing features of a common laboratory fruit fly with its rarer cousin collected from Hawai’i Volcanoes National Park, UC San Diego researchers used CRISPR technology to uncover clues about how high-level control genes called Hox genes shape our appearance.

Size Matters for Bee ‘Superorganism’ Colonies

November 10, 2021

Researchers studying honey bees have found that colony size matters in determining how members make decisions in the face of dynamic survival conditions. Large, established colonies are less likely to take chances while smaller colonies are much more willing to take risks.
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