April 13, 2017
April 13, 2017 —
Chinese hamster ovary (CHO) cells are the workhorses behind more than half of the top-selling biologics on the market today. Humira, Avastin and Rituxan are a few. Researchers at the UC San Diego CHO Systems Biology Center are developing new tools, such as genome-scale metabolic models, to optimize CHO cell production of biologic drugs in the hope of driving down their costs.
April 13, 2017
April 13, 2017 —
Optimizing CHO (Chinese hamster ovary) cell lines to accelerate biologic drug development is a goal of the CHO Systems Biology Center at the University of California San Diego Jacobs School of Engineering. Center researchers are developing new technologies and training the next generation of cell line engineers and systems biology specialists to advance CHO cell engineering research.
April 11, 2017
April 11, 2017 —
A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine detail. The new nanowire technology could one day serve as a platform to screen drugs for neurological diseases and could enable researchers to better understand how single cells communicate in large neuronal networks.
March 23, 2017
March 23, 2017 —
Researchers have developed a wearable, flexible biosensor glove that can rapidly detect toxic nerve agents with the touch of a finger. The so-called "lab-on-a-glove" could help improve both defense and food security measures. The team, led by nanoengineers at the University of California San Diego, published their work this month in ACS Sensors.
March 6, 2017
March 6, 2017 —
Bioengineers at the University of California San Diego have developed a new blood test that could detect cancer — and locate where in the body the tumor is growing. The study could provide a way to diagnose cancer early on without having to do invasive surgical procedures like biopsies.
March 2, 2017
March 2, 2017 —
In the past decade, UC San Diego engineers have 3D printed a variety of devices ranging from rocket engines, to robots, to structures inspired by the seahorse’s tail. Now, nanoengineers have added a new item to that list: a 3D printed blood vessel network.
March 2, 2017
March 2, 2017 —
Biofuel cells that are powered by human sweat. 3D printed heart tissue. Tiny robots that could deliver drugs. Stretchable and wearable electronics. These are just a few ways that nanoengineers at UC San Diego are making a big splash—at the nanoscale level.
February 28, 2017
February 28, 2017 —
How strongly tumor cells adhere to surrounding tissue could indicate how likely cancer will spread to other parts of the body, according to a new study led by bioengineers at the University of California San Diego. Using a spinning disc device, the researchers found that tumor cells that adhere weakly are more likely to migrate and invade other tissues compared with strongly adherent cells.
February 24, 2017
February 24, 2017 —
Bioengineers at the University of California San Diego have developed a new tool to identify RNA-DNA interactions. The tool can provide a full account of all the RNA molecules that interact with a segment of DNA, as well as the locations of all these interactions — in just a single experiment. The research is a step toward identifying new functions and instructions encoded in the genome.
February 16, 2017
February 16, 2017 —
Engineers at the University of California San Diego have developed a material that could reduce signal losses in photonic devices. The advance has the potential to boost the efficiency of various light-based technologies including fiber optic communication systems, lasers and photovoltaics.