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News Archive - Christina Johnson

Recipe for Wellness

May 14, 2015

What if there were a nearly universal prescription for better health, one that could save untold thousands of lives annually, lower health care costs and even help shrink the nation’s carbon footprint?

How to Reset a Diseased Cell

May 1, 2015

In proof-of-concept experiments, researchers at University of California, San Diego School of Medicine demonstrate the ability to tune medically relevant cell behaviors by manipulating a key hub in cell communication networks. The manipulation of this communication node, reported in this week’s issue of Proceedings of the National Academy of Sciences, makes it possible to reprogram large parts of a cell’s signaling network instead of targeting only a single receptor or cell signaling pathway.

Novel Approach Blocks Amyloid Production in Alzheimer’s Mouse Model

April 29, 2015

Offering a potential early intervention for Alzheimer’s disease (AD), researchers at University of California, San Diego School of Medicine and Cenna Biosciences, Inc. have identified compounds that block the production of beta amyloid peptides in mice. The study is reported April 29 in PLOS ONE.


Golgi Trafficking Controlled by G-Proteins

April 9, 2015

A family of proteins called G proteins are a recognized component of the communication system the human body uses to sense hormones and other chemicals in the bloodstream and to send messages to cells. In work that further illuminates how cells work, researchers at University of California, San Diego School of Medicine have discovered a new role for G proteins that may have relevance to halting solid tumor cancer metastasis.

Deconstructing Brain Systems Involved in Memory and Spatial Skills

April 2, 2015

In work that reconciles two competing views of brain structures involved in memory and spatial perception, researchers at University of California, San Diego School of Medicine have conducted experiments that suggest the hippocampus – a small region in the brain’s limbic system – is dedicated largely to memory formation and not to spatial skills, such as navigation. The study is published in this week’s issue of the Proceedings of the National Academy of Sciences.

Boosting A Natural Protection Against Alzheimer’s Disease

March 12, 2015

Researchers at the University of California, San Diego School of Medicine have identified a gene variant that may be used to predict people most likely to respond to an investigational therapy under development for Alzheimer’s disease (AD). The study, published March 12 in Cell Stem Cell, is based on experiments with cultured neurons derived from adult stem cells.

Understanding How Neurons Shape Memories of Smells

March 9, 2015

In a study that helps to deconstruct how olfaction is encoded in the brain, neuroscientists at University of California, San Diego School of Medicine have identified a type of neuron that appears to help tune, amplify and dampen neuronal responses to chemosensory inputs from the nasal cavity.

Obese Children’s Brains More Responsive to Sugar

December 11, 2014

A new study led by researchers at University of California, San Diego School of Medicine finds that the brains of obese children literally light up differently when tasting sugar.

First Angioedema Treatment Center Opens at UC San Diego Health System

November 24, 2014

UC San Diego Health System in partnership with the U.S. Hereditary Angioedema Association (HAEA), a non-profit patient advocacy organization, has opened the nation’s first dedicated center for diagnosing and treating diverse forms of swelling, known collectively as angioedema.

Sleep Apnea Linked to Poor Aerobic Fitness

November 24, 2014

People with moderate to severe obstructive sleep apnea may have an intrinsic inability to burn high amounts of oxygen during strenuous aerobic exercise according to a new study led by researchers at University of California, San Diego School of Medicine.
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