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Your search for “rare diseases” returned 216 results

Molecular “Brake” Prevents Excessive Inflammation

February 25, 2016

Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as…

Kids With MIS-C Mount Normal T Cell Response to COVID-19

October 7, 2021

UC San Diego study suggests multisystem inflammatory syndrome in children (MIS-C), a rare condition associated with COVID-19, is not caused by abnormal T cell response to COVID-19 virus as previously hypothesized.

The Key (Proteins) to Self-Renewing Skin

July 5, 2012

In the July 6 issue of Cell Stem Cell, researchers at the University of California, San Diego School of Medicine describe how human epidermal progenitor cells and stem cells control transcription factors to avoid premature differentiation, preserving their ability to produce new skin cells throughout life.

Mouse Model Yields Possible Treatment for Autism-Like Symptoms in Rare Disease

March 16, 2016

…with Jacobsen syndrome, a rare inherited disease, experience social and behavioral issues consistent with autism spectrum disorders. Researchers at University of California, San Diego School of Medicine and collaborators developed a mouse model of the disease that also exhibits autism-like social behaviors and used it to unravel the molecular mechanism…

Father’s Life is Saved after Receiving Heart, Kidney and Liver Transplant

September 8, 2022

After a rare disease caused organ failure, UC San Diego Heath transplant teams performed a heart, liver and kidney transplant on a patient. The surgery is a first for UC San Diego Health and a first in the nation to use three organs from a donor after circulatory death.

Though Risk is Minuscule, Infection after COVID-19 Vaccination is Possible

March 23, 2021

Investigators from UC San Diego and UCLA report COVID-19 infection rates for a cohort of health care workers previously vaccinated for the novel coronavirus. Risk of infection is minuscule, but exists.

Targeting Molecular Pathway that Causes Pulmonary Arterial Hypertension

May 6, 2022

UC San Diego researchers describe the underlying signaling pathway that results in pulmonary arterial hypertension and a novel monoclonal antibody therapy that blocks the abnormal blood vessel formation characterizing the disease.

A Dose of Research

March 23, 2017

…and education in neglected diseases and underserved patient populations Doctorate of pharmacy graduates typically follow paths that lead them to a career as a pharmacist in a hospital or community pharmacy, or as a researcher in academia or a pharmaceutical company. For Jincheng Yang, a student in the Skaggs School…

Researchers Create Model of Anorexia Nervosa Using Stem Cells

March 14, 2017

An international research team, led by scientists at University of California San Diego School of Medicine, has created the first cellular model of anorexia nervosa (AN), reprogramming induced pluripotent stem cells (iPSCs) derived from adolescent females with the eating disorder.

The Eyes Have It

November 20, 2018

Researchers at University of California San Diego School of Medicine with colleagues at the National Institutes of Health and UC San Francisco report finding infectious agent in the eyes of deceased sCJD patients, making the eye a potential source for early CJD detection and prevention of disease.

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