February 6, 2017
In a mouse study, researchers at University of California San Diego School of Medicine have identified a protein that inhibits the enzyme that breaks down bilirubin in newborns. Methods that block this inhibitor, and thus restore the enzyme’s activity, could provide a new therapeutic approach for preventing or treating severe…
July 26, 2012
…his life to pancreatic cancer. As a professor of pharmacology, chemistry and biochemistry at UC San Diego and a Howard Hughes Medical Institute investigator, he has worked to develop a novel way to image and possibly even deliver specially targeted drugs to cancer tumors.
January 22, 2015
Upending decades-old dogma, a team of scientists at the University of California, San Diego School of Medicine say enzymes long categorized as promoting cancer are, in fact, tumor suppressors and that current clinical efforts to develop inhibitor-based drugs should instead focus on restoring the enzymes’ activities.
November 1, 2012
…San Diego professor of pharmacology, chemistry and biochemistry Roger Tsien, won the Nobel Prize for chemistry (with Martin Chalfie and Osamu Shimomura) for their ground-breaking research in developing green fluorescent proteins derived from a bioluminescent jellyfish. Much of the acclaim that followed celebrated the novel possibilities of being able to…
September 29, 2011
A major risk factor for cardiovascular disease, type 2 diabetes and other health- and life-threatening conditions, obesity is epidemic in the United States and other developed nations where it’s fueled in large part by excessive consumption of a fat-rich “Western diet.”
November 23, 2020
Triclosan, an antimicrobial found in many soaps and other household items, worsens fatty liver disease in mice fed a high-fat diet.
December 17, 2012
Turning vast amounts of genomic data into meaningful information about the cell is the great challenge of bioinformatics, with major implications for human biology and medicine. Researchers at the University of California, San Diego School of Medicine and colleagues have proposed a new method that creates a computational model of…
October 24, 2013
…Ph.D. in physiology and pharmacology from UC San Diego. Eventually, he wound up fulfilling his destiny as one of the world’s most renowned bio geneticists, led by his unraveling of genome sequencing and the creation of “synthetic life.” In science-speak, this startling discovery holds the promise of having a profound…
October 14, 2013
The Leukemia & Lymphoma Society has awarded Thomas J. Kipps, MD, PhD, Distinguished Professor of Medicine at the University of California, San Diego School of Medicine, with a 5-year, $6.25 million Specialized Center of Research program grant to support research on chronic lymphocytic leukemia.
November 27, 2013
A key pillar of “the scientific method” is reproducibility, one way to prove another scientist’s experimental claims. If the experiment and its results can be reproduced, the validity of the work is considerably strengthened.
