October 26, 2022
Researchers at UC San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs. The discovery opens the possibility of new therapies, including for multiple forms of cancer.
September 27, 2011
A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of how this process works could have important implications for numerous diseases, including cancer and…
April 30, 2014
Researchers at the University of California, San Diego School of Medicine report that a protein called beta-catenin plays a critical, and previously unappreciated, role in promoting recovery of stricken hematopoietic stem cells after radiation exposure.
September 25, 2012
Researchers at University of California, San Diego Moores Cancer Center are evaluating the safety and tolerability of a synthetic cannabinoid called dexanabinol (ETS2101). Delivered as a weekly intravenous infusion, the drug is being tested in patients with all forms of brain cancer, both primary and metastatic.
June 17, 2013
A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which promotes cell survival, is essential for normal heart function.
January 25, 2012
Researchers at the University of California, San Diego School of Medicine have created a new generation of fast-acting fluorescent dyes that optically highlight electrical activity in neuronal membranes. The work is published in this week’s online Early Edition of the Proceedings of the National Academy of Sciences.
April 11, 2024
University of California San Diego solidified its status as a national leader in National Institutes of Health (NIH) funding, as reported by the 2023 Blue Ridge Institute for Medical Research (BRIMR) rankings.
August 13, 2015
Protein Kinase C is a family of enzymes that controls the activity of other proteins in a cell by attaching chemical tags. That simple act helps determine cell survival or death. When it goes awry, a number of diseases may result. In a study, researchers at University of California, San…
July 16, 2013
…Health Sciences, and Sandra and Monroe Trout Professor of Pharmacology at the University of California, San Diego, has been awarded the rank of “Chevalier dans l’Ordre national de la Légion d’Honneur” by the President of France, François Hollande.
March 20, 2019
UC San Diego School of Medicine research sets the stage for clinicians to potentially one day use levels of a pancreatic cancer patient’s PHLPP1 and PKC enzymes as a prognostic, and for researchers to develop new therapeutic drugs that inhibit PHLPP1 and boost PKC as a means to treat the…
