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Your search for “drug discovery” returned 453 results

New Computational Strategy Finds Brain Tumor-Shrinking Molecules

October 30, 2015

…search for molecules that could be developed into glioblastoma drugs. In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half. The study is published October 30 by Oncotarget.

Nuclei-free Cells Prove Utility in Delivering Therapeutics to Diseased Tissues

January 14, 2022

UC San Diego researchers report successfully removing the nucleus from a type of ubiquitous cell, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues.Researchers at University of California San Diego School of Medicine and Moores

Artificial Intelligence Could Be New Blueprint for Precision Drug Discovery

July 12, 2021

Researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

Novel Imaging Model Helps Reveal New Therapeutic Target for Pancreatic Cancer

June 6, 2016

…new model that not only allowed them to track drug resistance in vivo, but also revealed a new therapeutic target.

Kit Pogliano: Q & A with New Dean of Biological Sciences

May 2, 2019

…company to accelerate new drug discovery in the pharmaceutical industry. Prior to becoming Dean of Biological Sciences, Pogliano served as dean of UC San Diego’s Graduate Division. What drew your interest in becoming Dean of Biological Sciences? Biological Sciences is a fantastic division. We have amazing faculty who perform novel,…

UC San Diego and GSK Collaborate to Eradicate Cancer Stem Cells, Treat Leukemia

July 8, 2015

…cancer stem cells. The collaboration is part of GSK’s Discovery Partnerships with Academia (DPAc) program, where academic partners become core members of drug-hunting teams. Catriona Jamieson, MD, PhD, associate professor of medicine and chief of the Division of Regenerative Medicine, will lead UC San Diego’s effort in the new DPAc…

Albert La Spada Receives Harrington Scholar Award to Combat Neurodegenerative Disease

September 21, 2015

Albert La Spada, MD, PhD, professor of pediatrics, cellular and molecular medicine and neurosciences at University of California, San Diego School of Medicine, has received a 2015 Harrington Scholar award to advance his work on a therapy for Spinocerebellar ataxia type 7 (SCA7), a rare but devastating neurological disorder that…

Scientists Discover Neurochemical Imbalance in Schizophrenia

September 11, 2014

Using human induced pluripotent stem cells (hiPSCs), researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California, San Diego have discovered that neurons from patients with schizophrenia secrete higher amounts of three neurotransmitters broadly implicated in a range of psychiatric disorders.

Old Drugs Find New Target For Treating Brain Tumor

November 18, 2011

Scientists at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center, in collaboration with colleagues in Boston and South Korea, say they have identified a novel gene mutation that causes at least one form of glioblastoma (GBM), the most common type of malignant…

Fail-Safe System May Lead to Cures for Inherited Disorders

September 15, 2011

Scientists at the University of California, San Diego School of Medicine have uncovered a previously unknown fail-safe (compensatory) pathway that potentially protects the brain and other organs from genetic and environmental threats.

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