September 25, 2013
A team of cancer researchers at the University of California, San Diego has identified the existence of precursor cells in early prostate cancers. These cells are resistant to androgen-deprivation therapy, and may drive the subsequent emergence of recurrent or metastatic prostate cancer.
January 19, 2023
UC San Diego researchers describe how pancreatic cancer stem cells leverage a protein in a family of proteins that normally suppress tumors to instead do the opposite, boosting their resistance to conventional treatments and spurring growth.
April 13, 2017
…CHO (Chinese hamster ovary) cell lines to accelerate biologic drug development is a goal of the CHO Systems Biology Center at the University of California San Diego Jacobs School of Engineering. Center researchers are developing new technologies and training the next generation of cell line engineers and systems biology specialists…
April 20, 2014
…responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells.
January 2, 2014
Researchers at the University of California, San Diego School of Medicine report that an oncogene dubbed ROR1, found on chronic lymphocytic leukemia (CLL) B cells but not normal adult tissues, acts as an accelerant when combined with another oncogene, resulting in a faster-developing, more aggressive form of CLL in mice.
May 23, 2024
UC San Diego biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new “gene atlas” with 4D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.
April 14, 2022
…storage within the intact cells of fruit flies. The new optical imaging tool from the lab of bioengineering professor Lingyan Shi at the University of California San Diego is already being used to untangle often discussed, yet mysterious, links between diet and things like obesity, diabetes and aging. The work…
December 10, 2012
Biologists at UC San Diego have succeeded in genetically engineering algae to produce a complex and expensive human therapeutic drug used to treat cancer. Their achievement opens the door for making these and other “designer” proteins in larger quantities and much more cheaply than can now be made from mammalian…
April 11, 2019
Chemistry & Biochemistry researchers at UC San Diego ventured into the tiny atomic world of protein molecules within cells with a technological approach never before applied. Their findings offer other researchers a new way to do their work.
July 9, 2012
The biological mechanism of sunburn – the reddish, painful, protective immune response from ultraviolet (UV) radiation – is a consequence of RNA damage to skin cells, report researchers at the University of California, San Diego School of Medicine and elsewhere in the July 8, 2012 Advance Online Publication of Nature…
