October 9, 2014
Pharmaceutical companies will collaborate with researchers at the University of California, San Diego to provide previously unreleased proprietary data for drug discovery through a new $3.7 million effort funded by the National Institutes for Health. The project, which is led by UC San Diego principal investigators Rommie Amaro, Victoria Feher…
January 18, 2022
Countering a rising antibiotic resistance crisis, doctors now prescribe combinations of antibiotics. Yet many risks are involved with such multi-drug combinations. Scientists have developed a way to help doctors evaluate outcomes for different drug pairs and boost the odds of successful treatment.
December 6, 2018
Researchers spent two years testing chemical compounds for their ability to inhibit the malaria parasite at an earlier stage in its lifecycle than most current drugs, revealing a new set of chemical starting points for the first drugs to prevent malaria instead of just treating the symptoms.
July 23, 2018
Like small-scale Legos clicking into place, nature autonomously puts together microscopic building blocks. Living systems are biochemical machines that excel at building and moving their parts. Just as machines need energy in some form to operate, living systems are energized by consuming “fuel”—substances or food—reliably. The human body, for example,…
January 11, 2018
…San Diego School of Medicine, with colleagues across the country and around the world, have used whole genome analyses and chemogenetics to identify new drug targets and resistance genes in 262 parasite cell lines of Plasmodium falciparum — protozoan pathogens that cause malaria — that are resistant to 37 diverse…
November 1, 2022
New study identifies that first-degree relatives of patients with nonalcoholic fatty liver disease with advanced fibrosis (scarring of the liver) are at a 15% risk of developing the condition.
September 16, 2015
Nanoparticles disguised as human platelets could greatly enhance the healing power of drug treatments for cardiovascular disease and systemic bacterial infections. These nanoparticles are capable of delivering drugs to targeted sites in the body — particularly injured blood vessels and organs infected by harmful bacteria. This targeted drug delivery greatly…
June 17, 2014
…at the University of California, San Diego School of Medicine report that an almost century-old drug approved for treating sleeping sickness also restores normal cellular signaling in a mouse model of autism, reversing symptoms of the neurological disorder in animals that were the human biological age equivalent of 30 years…
November 8, 2024
Researchers at UC San Diego identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed early.
June 17, 2024
U.S. News & World Report has unveiled its 2024 Best Graduate Schools rankings in Engineering and in Pharmacy, spotlighting the UC San Diego Jacobs School of Engineering and Skaggs School of Pharmacy and Pharmaceutical Sciences as among the top in the nation.
