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Your search for “Rare Diseases” returned 233 results

The Key (Proteins) to Self-Renewing Skin

July 5, 2012

In the July 6 issue of Cell Stem Cell, researchers at the University of California, San Diego School of Medicine describe how human epidermal progenitor cells and stem cells control transcription factors to avoid premature differentiation, preserving their ability to produce new skin cells throughout life.

Single Enzyme’s Far-Reaching Influence in Human Biology and Disease

June 18, 2015

Researchers at University of California, San Diego School of Medicine have made a surprisingly simple discovery: The modification of more than 100 secreted proteins is the work of a single enzyme called Fam20C. The finding is published June 18 by Cell.

Dangerous Airborne Fungus Boosted by California Droughts

September 3, 2024

Researchers from UC San Diego and UC Berkeley have identified the seasonal and climate-based cycles of Valley fever, an emerging but dangerous fungal disease spread through dust in the air.

Blood Biopsy Reveals Unique, Targetable Genetic Alterations in Patients with Rare Cancer

August 15, 2017

Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a rare disease with seven to 12 cases per 100,000 people each year.

UC San Diego Health Ranked #1 by U.S. News & World Report

July 26, 2021

UC San Diego Health, the region’s only academic health system, is ranked #1 in San Diego and #5 in California, placing it among the nation’s best hospitals, according to the 2021-2022 U.S. News & World Report survey. UC San Diego Health was ranked in the top 50 in 10 specialties.

Molecular “Brake” Prevents Excessive Inflammation

February 25, 2016

Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as…

Cancer Drug and Antidepressants Provide Clues for Treating Fatal Brain-Eating Amoeba Infections

September 13, 2018

Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved…

Long-Reads and Powerful Algorithms Identify “Invisible” Microbes

January 3, 2022

Researchers have shown that highly accurate, long-read genomic sequencing technology (HiFi), combined with advanced algorithms, can differentiate between nearly identical organisms, allowing researchers to more completely catalogue microbial communities.

New Look at an Ancient Disease: Study Finds Novel Treatment Targets for Gout

December 13, 2022

UC San Diego scientists identify a new molecular model and potential therapeutic target for gout, the most common form of inflammatory arthritis.

Mother Delivers Baby, Develops Heart Disease

March 11, 2014

Three weeks after delivering her first child, Amanda began to suffer from extreme fatigue, headaches, a tight chest and stomach pain. An initial diagnosis of pneumonia changed for the worse: Amanda was experiencing heart failure. She was quickly transferred to UC San Diego Sulpizio Cardiovascular Center where a multidisciplinary team…

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