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Your search for “Pharmacology” returned 282 results

Clinical Trial Evaluates Synthetic Cannabinoid as Brain Cancer Treatment

September 25, 2012

Researchers at University of California, San Diego Moores Cancer Center are evaluating the safety and tolerability of a synthetic cannabinoid called dexanabinol (ETS2101). Delivered as a weekly intravenous infusion, the drug is being tested in patients with all forms of brain cancer, both primary and metastatic.

Study Identifies Protein Essential for Normal Heart Function

June 17, 2013

A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which promotes cell survival, is essential for normal heart function.

New Fluorescent Dyes Highlight Neuronal Activity

January 25, 2012

Researchers at the University of California, San Diego School of Medicine have created a new generation of fast-acting fluorescent dyes that optically highlight electrical activity in neuronal membranes. The work is published in this week’s online Early Edition of the Proceedings of the National Academy of Sciences.

Corrected Protein Structure Reveals Drug Targets for Cancer, Neurodegenerative Diseases

August 13, 2015

Protein Kinase C is a family of enzymes that controls the activity of other proteins in a cell by attaching chemical tags. That simple act helps determine cell survival or death. When it goes awry, a number of diseases may result. In a study, researchers at University of California, San…

UC San Diego’s Palmer Taylor Awarded France’s Legion of Honour

July 16, 2013

…Health Sciences, and Sandra and Monroe Trout Professor of Pharmacology at the University of California, San Diego, has been awarded the rank of “Chevalier dans l’Ordre national de la Légion d’Honneur” by the President of France, François Hollande.

Balance of Two Enzymes Linked to Pancreatic Cancer Survival

March 20, 2019

UC San Diego School of Medicine research sets the stage for clinicians to potentially one day use levels of a pancreatic cancer patient’s PHLPP1 and PKC enzymes as a prognostic, and for researchers to develop new therapeutic drugs that inhibit PHLPP1 and boost PKC as a means to treat the…

Researchers Unfold New Details About a Powerful Protein

October 9, 2014

Using X-rays and neutron beams, a team of researchers from the University of California, San Diego School of Medicine, University of Utah and Oak Ridge National Laboratory have teased out new information about Protein Kinase A (PKA), a ubiquitous master switch that helps regulate fundamental cellular functions like energy consumption…

Oncogene Mutation Hijacks Splicing Process to Promote Growth and Survival

May 31, 2013

An international team of researchers – led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine – has found that a singular gene mutation helps brain…

Roche Funds Drug Discovery Projects at UC San Diego

January 9, 2012

The new UC San Diego-Roche Extending Innovation Network (EIN) program has been launched with selection of its first three research projects at the University of California, San Diego School of Medicine.

Lactating Mice Pass along Common Antimicrobial to Pups, Initiating Liver Damage

July 27, 2022

In mouse studies, UC San Diego researchers report that lactating mothers expose their feeding pups to triclosan, an antimicrobial commonly used in consumer products, resulting in early signs of liver damage.

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