September 12, 2013
Researchers at the Pediatric Diabetes Research Center (PDRC) at the University of California, San Diego School of Medicine have shown that the pancreatic protein Nkx6.1 – a beta-cell enriched transcription factor – is essential to maintaining the functional state of beta cells.
April 21, 2023
UC San Diego researchers describe a key player in the defense mechanism that safeguards against excessive insulin in the body, which can be as harmful as too little.
May 2, 2017
…by producing the hormone insulin — the master regulator of energy (glucose). Impairment and the loss of beta cells interrupts insulin production, leading to type 1 and 2 diabetes. Using single-cell RNA sequencing, researchers at University of California San Diego School of Medicine have, for the first time, mapped out…
May 1, 2012
…exploring: the complex interactions of lipids and inflammation in insulin resistance; the roles of omega 3 fatty acids and a particular gene in fighting inflammation;how elevated levels of a particular protein might delay the muscle-destroying effects of amyotrophic lateral sclerosis.
July 6, 2015
Alan R. Saltiel, PhD, whose studies of the hormone insulin have helped drive research of obesity, diabetes and other metabolic disorders across the nation, is joining University of California, San Diego School of Medicine as professor and director of a new Comprehensive Diabetes Center.
September 9, 2014
Researchers at the University of California, San Diego School of Medicine, in partnership with ViaCyte, Inc., a San Diego-based biotechnology firm specializing in regenerative medicine, have launched the first-ever human Phase I/II clinical trial of a stem cell-derived therapy for patients with Type 1 diabetes.
January 25, 2021
University of California San Diego School of Medicine and Moores Cancer Center researchers report that intermittent fasting reduced breast cancer risk in obese mice.
November 10, 2011
By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically boosted insulin sensitivity in lab mice, an achievement that opens a new door for drug development and the treatment of diabetes.
June 5, 2014
Researchers at the University of California, San Diego School of Medicine have, for the first time, described the sequence of early cellular responses to a high-fat diet, one that can result in obesity-induced insulin resistance and diabetes. The findings also suggest potential molecular targets for preventing or reversing the process.
November 3, 2015
…built environment and biomarkers of cancer risk, such as insulin resistance and inflammation.
