January 15, 2015
…previously reported that a drug used for almost a century to treat trypanosomiasis, or sleeping sickness, reversed environmental autism-like symptoms in mice. Now, a new study published in this week’s online issue of Molecular Autism, suggests that a genetic form of autism-like symptoms in mice are also corrected with the…
October 4, 2012
…molecular approach to delivering drugs that could change the pharmaceutical industry worldwide. The W.M. Keck Foundation of Los Angeles supports “high risk/high reward” pioneering discoveries in groundbreaking studies that enable researchers to translate their innovative ideas into real world impact. Steve Dowdy, a professor in the department of cellular and…
January 5, 2021
Researchers describe the biology of three families of RNA viruses including Coronavirus, Ebola, and Zika and the natural products that have been shown to have capabilities to inhibit them. The review provides a guide that could accelerate drug discovery in response to future epidemics.
December 17, 2020
New simulations done on supercomputers may help researchers understand how these inhibitors react and potentially help to develop a new generation of drugs to target viruses with high death rates including SARS-CoV2, the virus that causes COVID-19.
October 29, 2018
…new way of re-sensitizing drug-resistant human tumor cells to the potency of DNA-damaging agents, the most widely used group of cancer drugs. In a new study, they describe how a human gene known as Schlafen 11 controls the sensitivity of tumor cells to DDAs. Their research may pave the way…
January 22, 2016
…hours, an advance that could slow the appearance of drug resistance and allow doctors to more rapidly identify the appropriate treatment for patients with life threatening bacterial infections.
February 26, 2015
…of the Center for Discovery and Innovation in Parasitic Diseases. An expert in the area of neglected tropical diseases, McKerrow has brought a wealth of experience in natural product research and drug discovery and development to UC San Diego. His keen interest in these areas brings together cross-disciplinary researchers across…
January 18, 2024
Cancer resists treatment in a multitude of ways, but a new algorithm developed by scientists at UC San Diego can decode them all simultaneously.
January 24, 2020
Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, UC San Diego researchers found that opioid dependence produced permanent changes in the brains of rats.
December 7, 2016
…together may better enable pharmaceutical companies to develop anti-inflammatory drugs that bind and inhibit CCR2 in a similar manner. The study is published December 7 by Nature.
