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Your search for “Drug discovery” returned 447 results

Single Dose Reverses Autism-like Symptoms in Mice

June 17, 2014

…Diego School of Medicine report that an almost century-old drug approved for treating sleeping sickness also restores normal cellular signaling in a mouse model of autism, reversing symptoms of the neurological disorder in animals that were the human biological age equivalent of 30 years old.

Big Data Sharing for Better Health

October 10, 2014

Researchers at University of California, San Diego School of Medicine have been awarded a $9.2 million grant to help modernize and transform how researchers share, use, find and cite biomedical datasets.

How to Reset a Diseased Cell

May 1, 2015

In proof-of-concept experiments, researchers at University of California, San Diego School of Medicine demonstrate the ability to tune medically relevant cell behaviors by manipulating a key hub in cell communication networks. The manipulation of this communication node, reported in this week’s issue of Proceedings of the National Academy of Sciences,…

Worms Reveal Secrets of Wound Healing Response

November 17, 2011

The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body’s response to healing skin wounds, a serious problem in diabetics and the elderly.

Breaking Ground

October 27, 2016

…mapping, advanced energy and drug discovery innovation. At the building groundbreaking, the campus announced a $2 million gift from The Kavli Foundation to support the project, which will be recognized with the naming of the Fred Kavli Auditorium in the new building. “This is a great day for the university,…

Bioinformatics Breakthrough: High Quality Transcriptome from as Few as Fifty Cells

October 24, 2013

…early stages, as well as better tools for forensics, drug discovery and developmental biology.

Discovery Could Lead to Novel Therapies for Fragile X Syndrome

April 17, 2014

Scientists studying the most common form of inherited mental disability—a genetic disease called “Fragile X syndrome”—have uncovered new details about the cellular processes responsible for the condition that could lead to the development of therapies to restore some of the capabilities lost in affected individuals.

Repurposed Asthma Drug Shows Blood Sugar Improvement among Some Diabetics

July 5, 2017

After 12 weeks of taking an anti-asthma drug, a subset of patients with type 2 diabetes showed a clinically significant reduction in blood glucose during a randomized, double blind, placebo-controlled clinical trial, report University of California San Diego School of Medicine and University of Michigan researchers.

How to Speed Up Muscle Repair

March 17, 2021

By studying how different pluripotent stem cell lines build muscle, researchers have for the first time discovered how epigenetic mechanisms can be triggered to accelerate muscle cell growth, providing new insights for developing therapies for muscle disease, injury and atrophy.

Supercomputer Simulations Reveal New “Achilles heel” in Dengue Virus

April 30, 2018

By stretching the amount of time proteins can be simulated in their natural state of wiggling and gyrating, a team of researchers at Colorado State University— using supercomputers at the San Diego Supercomputer Center at UC San Diego and the Pittsburgh Supercomputing Center—has identified a critical protein structure that could…

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