June 25, 2020
Researchers from Harvard University and the University of Texas Medical Branch at Galveston recently used the Comet supercomputer at the San Diego Supercomputer Center at the University of California San Diego to uncover the novel ways in which DNA prepares itself for repair.
December 19, 2013
Researchers at the University of California, San Diego School of Medicine, with colleagues in The Netherlands and United Kingdom, have produced the first map detailing the network of genetic interactions underlying the cellular response to ultraviolet (UV) radiation.
December 22, 2011
In eukaryotes – the group of organisms that include humans – a key to survival is the ability of certain proteins to quickly and accurately repair genetic errors that occur when DNA is replicated to make new cells.
August 22, 2018
In a paper published this week in the journal PNAS, researchers at University of California San Diego School of Medicine, with colleagues in Spain and Finland, describe for the first time how one type of RNA polymerase gets stalled by DNA lesions caused by exposure to ultraviolet (UV) light.
July 1, 2022
Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.
October 29, 2018
…to the potency of DNA-damaging agents, the most widely used group of cancer drugs. In a new study, they describe how a human gene known as Schlafen 11 controls the sensitivity of tumor cells to DDAs. Their research may pave the way to new strategies to overcome chemotherapeutic drug resistance.
March 17, 2016
…Medicine have now achieved this by applying the popular DNA-editing technique CRISPR-Cas9 to RNA. The study is published March 17 in Cell.
June 15, 2022
The science behind predicting your viewing habits on Netflix could one day be used to guide doctors in managing some of the hardest-to-treat cancers, shows a study led by the University of California San Diego and University College London.
May 22, 2023
UC San Diego scientists develop an interactive software that enables scientists to better investigate the DNA damage response.
June 15, 2023
UC San Diego scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations
