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Your search for “Cancer” returned 1418 results

Topography of the Genome Influences Where Cancer Mutations Thrive, Study Shows

August 24, 2023

Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer. Certain regions of the genome, which exhibit unique features, act as hotspots for the accumulation of mutations.

Short Overnight Fasting Linked to Increased Risk of Breast Cancer Recurrence

March 31, 2016

In patients with breast cancer, a short overnight fast of less than 13 hours was associated with a statistically significant, 36 percent higher risk of breast cancer recurrence and a non-significant, 21 percent higher probability of death from the disease compared to patients who fasted 13 or more hours per…

Opposite Effect: Protein Widely Known to Fight Tumors Also Boosts Cancer Growth

January 31, 2019

UC San Diego researchers studying p53, the heralded cancer-fighting “guardian of the genome,” found that the human protein also plays a role in promoting tumors, in addition to suppressing them.

In Cells, UV-Emitting Nail Polish Dryers Damage DNA and Cause Mutations

January 17, 2023

The ultraviolet nail polish drying devices used to cure gel manicures may pose more of a public health concern than previously thought. Researchers at UC San Diego studied these UV light-emitting devices, and found that their use leads to cell death and cancer-causing mutations in human cells.

Developmental Protein Plays Role in Spread of Cancer

June 14, 2013

…development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center in the June 15, 2013 issue of the…

Antibody Drug Conjugates May Help Personalize Radiotherapy for Patients with Cancer

October 4, 2016

Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects.

Harnessing Cancer’s Methylation Footprint for More Precise Diagnosis and Prognosis

June 27, 2017

…Medicine, with colleagues in Xijing Hospital and Sun Yat-sen Cancer Center in China, report that DNA methylation can provide effective markers for at least four major cancers, not only correctly differentiating malignant tissues from normal, but also providing information on prognosis and survival.

Tumor Suppressor Mutations Alone Don’t Explain Deadly Cancer

August 3, 2014

…recognized as being associated with more aggressive forms of cancer, researchers at the University of California, San Diego School of Medicine have found evidence suggesting that the deleterious health effects of the mutated gene may in large part be due to other genetic abnormalities, at least in squamous cell head…

UC San Diego Study Points to Virus-Related Acceleration in Some Cancers

March 14, 2019

A new paper by UC San Diego researchers hypothesizes a possible link between cancer-causing viruses.

Gene Mutation “Hotspots” Linked to Better Breast Cancer Outcomes

June 30, 2016

…of Medicine and Moores Cancer Center discovered that mutation hotspots known as kataegis are a positive marker in breast cancer — patients with kataegis have less invasive tumors and better prognoses. The study, published June 30 in Cell Reports, also suggests kataegis status could help doctors determine treatment options that…

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