October 18, 2023
UC San Diego engineers have developed an experimental vaccine that could prevent the spread of metastatic cancers to the lungs. Its success lies in targeting a protein known to play a central role in cancer growth and spread, rather than targeting the primary tumor itself.
September 16, 2014
Researchers at the University of California, San Diego School of Medicine have launched a phase 1 human clinical trial to assess the safety and efficacy of a new monoclonal antibody for patients with chronic lymphocytic leukemia (CLL), the most common form of blood cancer in adults.
April 10, 2014
…on his research of cancer metastasis. Aung studies metastasis from a biophysics perspective, trying to understand how cancer cells push, pull and tear through endothelial cells (the cells lining the blood vessels) to escape blood vessels and migrate within the underlying tissues. By understanding these forces in connection with biological…
December 11, 2017
…play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, report University of California San Diego School of Medicine and Moores Cancer Center researchers.
February 27, 2018
…of California San Diego School of Medicine and Moores Cancer Center describe how a signaling protein that normally suppresses tumors can be manipulated (or re-programmed) by growth factors, turning it into a driver of malignant growth and metastasis.
February 26, 2016
Researchers at University of California, San Diego School of Medicine and Moores Cancer Center, with colleagues in Spain and Germany, have unraveled how elevated levels of particular proteins in cancer cells trigger hyperactivity in other proteins, fueling the growth and spread of a variety of cancers.
April 20, 2014
…lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a biomarker called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of…
April 9, 2015
…proteins that may have relevance to halting solid tumor cancer metastasis.
January 25, 2021
University of California San Diego School of Medicine and Moores Cancer Center researchers report that intermittent fasting reduced breast cancer risk in obese mice.
December 21, 2015
…Diego School of Medicine and UC San Diego Moores Cancer report that a protein called Wnt5a acts on a pair of tumor-surface proteins, called ROR1 and ROR2, to accelerate the proliferation and spread of chronic lymphocytic leukemia (CLL) cells, the most common form of blood cancer in adults.
