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Your search for “Animal Models” returned 337 results

Diet Plays Critical Role in NASH Progressing to Liver Cancer in Mouse Model

June 1, 2021

Researchers at University of California San Diego School of Medicine found in a mouse model that when fed a Western diet rich in calories, fat and cholesterol, the mice progressively became obese, diabetic and developed NASH, which progressed to HCC, chronic kidney and cardiovascular disease.

Blocking Digestive Enzymes May Reverse Shock, Stop Multiorgan Failure

January 23, 2013

New research from the University of California, San Diego published in the Jan. 23 issue of Science Translational Medicine moves researchers closer to understanding and developing treatments for shock, sepsis and multiorgan failure. Collectively, these maladies represent a major unmet medical need: they are the number one cause of mortality…

Surgical Technique Spots Cancer Invasion with Fluorescence

January 10, 2013

A team of surgeons and scientists at University of California, San Diego School of Medicine have developed a new technique that will allow surgeons to identify during surgery which lymph nodes are cancerous so that healthy tissue can be saved. The findings will be published in the January 15 print…

Nanospheres Safely Deliver High Chemotherapy Doses in Response to Tumor Secretions

July 14, 2015

Scientists have designed nanoparticles that release drugs in the presence of a class of proteins that enable cancers to metastasize. That is, they have engineered a drug delivery system so that the very enzymes that make cancers dangerous could instead guide their destruction.

UC San Diego Health Launches Clinical Trial to Assess Antiviral Drug for COVID-19

March 24, 2020

Researchers at four University of California Health medical centers have begun recruiting participants for a Phase II clinical trial to investigate the safety and efficacy of treating adult patients with COVID-19 with remdesivir, a drug that has shown promising activity against multiple viruses.

A Map for the Sense of Smell

January 28, 2022

Our sensory systems provide us with immediate information about the world around us. Researchers have created the first sensory map for smell. The map details how the fruit fly’s olfactory receptor neurons, the components that sense smell, are organized within the insect’s sensory hairs.

New Study Looks at How the “Blob” Came Back

April 21, 2020

Weakened wind patterns likely spurred the wave of extreme ocean heat that swept the North Pacific Ocean last summer, according to new research led by researchers at the University of Colorado Boulder and Scripps Institution of Oceanography at UC San Diego.

Department of Philosophy Professor Wins 2018 Lakatos Award

August 22, 2018

…Makes Time Special?” tackles the conflict between our intuitive model of time as flowing and the “static” time of fundamental physics.

It’s Not a Rat’s Race for Human Stem Cells Grafted to Repair Spinal Cord Injuries

August 28, 2017

More than one-and-a-half years after implantation, researchers at University of California San Diego School of Medicine and the San Diego Veterans Administration Medical Center report that human neural stem cells (NSCs) grafted into spinal cord injuries in laboratory rats displayed continued growth and maturity, with functional recovery beginning one year…

Nanoengineers Receive $4.3M From NIH To Continue Studies Using Plant Viruses To Treat Cancer

October 17, 2022

Researchers led by Nicole Steinmetz, professor of nanoengineering at the University of California San Diego, have received $4.3 million in grants from the National Institutes of Health (NIH) to advance their research using plant viruses to develop cancer immunotherapies.

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