August 21, 2023
New results from researchers at UC San Diego School of Medicine suggest that intermittent fasting could be an effective treatment approach for Alzheimer’s disease. Mice fed on a time-restricted schedule had better memory and less accumulation of amyloid proteins in the brain compared to controls.
February 19, 2013
…between neurons, and describe how a compound linked to Alzheimer’s disease impacts that receptor and weakens synaptic connections between brain cells.
April 23, 2024
Using state-of-the-art microscopy techniques developed on campus, researchers at UC San Diego School of Medicine have shed new light on the underlying mechanisms driving Alzheimer’s disease.
March 31, 2020
UC San Diego researchers discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection of Alzheimer’s. The work could lead to the development of a blood test to identify individuals who will develop the disease years before they show symptoms.
September 17, 2015
…Americans are living with Alzheimer’s disease (AD). Of them, 400,000 also have Down syndrome. Both groups have similar looking brains with higher levels of the protein beta amyloid. In fact, patients with Down syndrome develop the abnormal protein at twice the rate. Results of a pilot study confirms the pathogenic…
May 10, 2016
In Alzheimer’s disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neurons. Now, researchers at University of California San Diego School of Medicine and Harvard Medical School have found that the enzyme Protein Kinase C (PKC) alpha is necessary for amyloid beta to damage neuronal connections.…
March 12, 2015
…to respond to an investigational therapy under development for Alzheimer’s disease (AD). The study, published March 12 in Cell Stem Cell, is based on experiments with cultured neurons derived from adult stem cells.
April 6, 2012
Researchers at the University of California, San Diego and Veterans Affairs San Diego Healthcare System have shown that elevated pulse pressure may increase the risk of cerebrovascular disease (CVD) in older adults with Alzheimer’s disease (AD).
December 15, 2022
Researchers at UC San Diego provide new insights into the pathology of limbic predominate age-related TDP-43 encephalopathy, which mimics Alzheimer’s, making it very difficult to identify in living patients.
May 3, 2022
…older adults could be an early warning sign of Alzheimer’s disease. Research led by UC San Diego has consistently found high levels of PHGDH expression in brain tissue and blood samples of older adults with different stages of the disease.
