Skip to main content

Your search for “Metabolic Disease” returned 265 results

Binding Sites for LIN28 Protein Found in Thousands of Human Genes

September 4, 2012

…and reprogramming as well as in cancer and other diseases. According to the researchers, their study – published in the September 6 online issue of Molecular Cell – will change how scientists view this protein and its impact on human disease.

How Obesity Dismantles Our Mitochondria

January 29, 2024

UC San Diego researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain. They also found they could reverse the effect by targeting a single gene, suggesting a new treatment strategy for…

Too Much of a Good Thing May Lead to Too Much of a Liver As Well

February 24, 2020

UC San Diego researchers suggest that prolonged exposure to a pair of antioxidant proteins may contribute to enlargement of the liver and fatty liver diseases.

Drug Treatment Corrects Autism Symptoms in Mouse Model

March 13, 2013

Autism results from abnormal cell communication. Testing a new theory, researchers at the University of California, San Diego School of Medicine have used a newly discovered function of an old drug to restore cell communications in a mouse model of autism, reversing symptoms of the devastating disorder.

Technique May Identify Patients with Fast-Progressing Fibrosis in Nonalcoholic Fatty Liver Disease

October 11, 2016

Combining multiple non-invasive measures, researchers at University of California San Diego School of Medicine describe a novel method to quantify the progression of nonalcoholic fatty liver disease (NAFLD) to its more dangerous and deadly states — advanced fibrosis and cirrhosis.

When — Not What — Obese Mice Ate Reduced Breast Cancer Risk

January 25, 2021

University of California San Diego School of Medicine and Moores Cancer Center researchers report that intermittent fasting reduced breast cancer risk in obese mice.

Enzyme Restores Function with Diabetic Kidney Disease

October 25, 2013

…cellular levels of glucose ultimately result in diabetic kidney disease, the truth may, in fact, be quite the opposite. The findings could fundamentally change understanding of how diabetes-related diseases develop – and how they might be better treated.

Spotting the Earliest Signs of Type 1 Diabetic Kidney Disease

October 22, 2015

In an effort to pinpoint the earliest signs of diabetic kidney disease, researchers at University of California, San Diego School of Medicine are leading a multi-institutional international effort dedicated to finding a new breed of disease indicators.

How Mitochondrial Damage Ignites the “Auto-Inflammatory Fire”

July 13, 2022

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and well-being.

Flipping a Metabolic Switch to Slow Tumor Growth

August 12, 2020

The enzyme serine palmitoyl-transferase can be used as a metabolically responsive “switch” that decreases tumor growth, according to a new study by a team of San Diego scientists, who published their findings Aug. 12 in the journal Nature.

Category navigation with Social links