Researchers at Harvard University and the University of California, San Diego, have developed a new user-friendly resource to accompany the powerful gene editing tool called CRISPR/Cas9, which has been widely adopted to make precise, targeted changes in DNA. This breakthrough has the potential to facilitate new discoveries in gene therapies and basic genetics research. The research was published in the July 13 issue of Nature Methods.
Light becomes trapped as it orbits within tiny granules of a crystalline material that has increasingly intrigued physicists, a team led by University of California, San Diego, physics professor Michael Fogler has found.
Scientists have designed nanoparticles that release drugs in the presence of a class of proteins that enable cancers to metastasize. That is, they have engineered a drug delivery system so that the very enzymes that make cancers dangerous could instead guide their destruction.
UC San Diego Health and AccentCare have created a jointly owned home health services agency to serve UC San Diego Health patients in San Diego and surrounding communities. The new agency is designed to provide a comprehensive continuum of care after patients have been discharged from the hospital to facilitate efficient communication, improved safety, and faster healing.
Tumors can leverage glucose and other nutrients to resist targeted therapies directed at specific cellular molecules, according to researchers at University of California, San Diego School of Medicine and Ludwig Cancer Research. In the study, published this week in Proceedings of the National Academy of Sciences, the team used human tissue and mouse models to demonstrate that nutrients can strongly affect the signaling molecules that drive tumors in glioblastoma, a deadly brain cancer.
From the smell of flowers to the taste of wine, our perception is strongly influenced by prior knowledge and expectations, a cognitive process known as top-down control. In a University of California, San Diego School of Medicine study, a research team led by Takaki Komiyama, PhD, assistant professor of neurosciences and neurobiology, reports that in mouse models, the brain significantly changed its visual cortex operation modes by implementing top-down processes during learning.