School of Medicine

The Latest

Most Patients Willing to Share Medical Records for Research Purposes

In a survey, UC San Diego researchers report most patients are willing to share medical records for research purposes, with a few caveats.

UC San Diego Researchers Convert Pro-Tumor Macrophages into Cancer Killers

University of California San Diego School of Medicine researchers identified a new therapeutic approach in mouse models that halts drug resistance and cancer progression by using an antibody that induces the immune system via macrophages to seek and kill cancer cells.

UC San Diego Receives $9 Million in Grants to Pinpoint Cellular Cause of Type 1 Diabetes

UC San Diego School of Medicine has been awarded $9 million to fund research projects using human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the cellular actions leading to disease onset.

Single Enzyme Helps Drive Inflammation in Mice, Provides Target for New Sepsis Drugs

UC San Diego researchers discovered that removing a single enzyme in mice dramatically boosts survival from sepsis, an often fatal over-reaction of the immune system to infection. The finding provides a new and unexpected therapeutic target for new drug development.

Adding MS Drug to Targeted Cancer Therapy May Improve Glioblastoma Outcomes

The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor’s root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.

Promising Clinical Trial Results for Drug for Rare Disease in Which Patients Can’t Eat Fat

In a Phase III clinical trial, the drug volanesorsen significantly reduced blood fat (triglyceride) levels in participants with a rare disease called familial chylomicronemia syndrome; finding could also help inform better prevention methods and treatments for many types of heart disease.