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News Archive - School of Medicine

Corrected Protein Structure Reveals Drug Targets for Cancer, Neurodegenerative Diseases

August 13, 2015

Protein Kinase C is a family of enzymes that controls the activity of other proteins in a cell by attaching chemical tags. That simple act helps determine cell survival or death. When it goes awry, a number of diseases may result. In a study, researchers at University of California, San Diego School of Medicine reveal a more accurate structure of PKC, providing new targets for fine-tuning the enzyme’s activity as needed to improve human health.

Newly Discovered Cells Regenerate Liver Tissue Without Forming Tumors

August 13, 2015

The mechanisms that allow the liver to repair and regenerate itself have long been a matter of debate. Now researchers at University of California, San Diego School of Medicine have discovered a population of liver cells that are better at regenerating liver tissue than ordinary liver cells, or hepatocytes. The study is the first to identify these so-called “hybrid hepatocytes,” and show that they are able to regenerate liver tissue without giving rise to cancer.

Novel Therapeutic Agent for Pediatric Cancer Developed at UC San Diego in Clinical Trials

August 11, 2015

Donald L. Durden, MD, PhD, pediatric researcher at University of California, San Diego School of Medicine and Moores Cancer Center has identified and developed a novel therapeutic target for neuroblastoma, the second most common solid-tumor childhood cancer. The agent, named SF1126, acts by inhibiting the part of the cancer cell engine that promotes tumor angiogenesis and growth.

Radiation Costs Vary Among Medicare Patients with Cancer

August 11, 2015

Cost of radiation therapy among Medicare patients varied most widely because of factors unrelated to a patient or that person’s cancer, report University of California, San Diego School of Medicine researchers in the Journal of Oncology Practice.

UC San Diego Undergraduate Awarded National Barry Goldwater Scholarship

August 7, 2015

University of California, San Diego undergraduate Angela Zou has been awarded the Barry M. Goldwater Scholarship, one of the most competitive and prestigious awards in the nation. From a field of 1,206 applicants, Zou was one of 260 students to receive the scholarship, and the only recipient from UC San Diego.

RIFFA Framework Seamlessly Connects Computer Processors with FPGAs

August 6, 2015

Students at the University of California, San Diego have created RIFFA, a simple framework for communicating data from a computer processor to a Field Programmable Gate Array (FPGA). The open-source technology, which can be used with any FPGA vendor on Windows or Linux, could lead to faster design times and higher profit margins for a wide range of industries. 

High Rates of Violence, HIV Infection for Adolescents in Sex Trade on U.S.-Mexico Border

August 4, 2015

Researchers at University of California, San Diego School of Medicine report that more than one in four female sex workers in two Mexican cities on the U.S. border entered the sex trade younger than age 18; one in eight before their 16th birthday. These women were more than three times more likely to become infected with HIV than those who started sex work as adults.

Genetic Adaptation Keeps Ethiopians Heart-Healthy Despite High Altitudes

August 3, 2015

Ethiopians have lived at high altitudes for thousands of years, providing a natural experiment for studying human adaptations to low oxygen, a condition known as hypoxia. One factor that may enable Ethiopians to tolerate high altitudes and hypoxia is the endothelin receptor type B (EDNRB) gene. Researchers at University of California, San Diego School of Medicine now find that mice with lower-than-normal levels of EDNRB protein are remarkably tolerant to hypoxia.

Researchers Illuminate Key Role of NOX Proteins in Liver Disease

July 29, 2015

Researchers at the University of California, San Diego School of Medicine have demonstrated a direct connection between two signaling proteins and liver fibrosis, a scarring process underlying chronic liver disease, the 12th leading cause of death in the United States.

Researchers Find Key Player in Diabetic Kidney Disease Through Power of Metabolomics

July 29, 2015

Tapping the potential of metabolomics, an emerging field focused on the chemical processes of metabolism, researchers at University of California, San Diego School of Medicine have identified a new and pivotal player in diabetic kidney disease.
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