October 10, 2017
October 10, 2017 —
Approximately 10 percent of Americans take a proton pump inhibitor drug to relieve symptoms of frequent heartburn and acid reflux. That percentage can be much higher for people with chronic liver disease. Researchers at University of California San Diego School of Medicine have discovered evidence in mice and humans that these medications alter gut bacteria in a way that promotes three types of chronic liver disease. The study is published October 10 in Nature Communications.
October 9, 2017
October 9, 2017 —
Researchers at University of California San Diego School of Medicine, with national collaborators, have identified a series of molecular clues to understanding the formation of cerebral cavernous malformations (CCMs). The study offers the first genome-wide analysis of the transcriptome of brain microvascular endothelial cells after KRIT1 inactivation.
October 9, 2017
October 9, 2017 —
An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood sample containing circulating tumor DNA.
October 3, 2017
October 3, 2017 —
Patients at UC San Diego Health in need of radiation therapy now have access to the next generation of radiation treatment technology. The new radiotherapy system significantly reduces treatment times with improved accuracy.
October 1, 2017
October 1, 2017 —
In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies.
September 29, 2017
September 29, 2017 —
Researchers at University of California San Diego School of Medicine have developed the first mice that lack the Upf3b gene, providing a new model for studying its underlying role in intellectual disabilities and neurodevelopmental disorders.
September 28, 2017
September 28, 2017 —
Using a form of low-impulse electrical stimulation to the brain, documented by neuroimaging, researchers at the University of California San Diego School of Medicine, Veterans Affairs San Diego Healthcare System (VASDHS) and collaborators elsewhere, report significantly improved neural function in participants with mild traumatic brain injury (TBI).
September 28, 2017
September 28, 2017 —
A team of researchers has engineered smart protein molecules that can reprogram white blood cells to ignore a self-defense signaling mechanism that cancer cells use to survive and spread in the body. Researchers say the advance could lead to a new method of re-engineering immune cells to fight cancer and infectious diseases. The team successfully tested this method in a live cell culture system.
September 27, 2017
September 27, 2017 —
Cancers driven by mutations in the KRAS gene are among the most deadly. For decades, researchers have tried unsuccessfully to directly target mutant KRAS proteins as a means to treat tumors. Instead of targeting mutant KRAS itself, researchers at University of California San Diego School of Medicine are now looking for other genes or molecules that, when inhibited, kill cancer cells only when KRAS is also mutated.
September 22, 2017
September 22, 2017 —
More than 100 physicians from UC San Diego Health were named “Top Docs” in the annual San Diego Magazine “Physicians of Exceptional Excellence” annual survey. These physicians represent 45 diverse specialties, from infectious disease, surgery and oncology to obstetrics, cardiology and emergency medicine.
