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News Archive - Biological Sciences

New Research Reveals How Location Influences How Our Immune System Fights Disease

January 22, 2025

A new study led by a team of scientists reveals how cells known as tissue-resident memory CD8 T cells play unique and specialized roles based on where they are located. The discovery sheds light on how such cells adapt to their location and could lead to improved immunotherapy and vaccines.

Epilepsy Patient Samples Offer Unprecedented Insights on Brain ‘Brakes’ Linked to Disorders

January 22, 2025

Specific protein receptors in the brain play a vital role in how neurons slow down or stop firing, making them targets for many disorders. Researchers have now constructed a detailed structural map of these receptors in the human brain, revealing how they assemble and how drugs bind to them.

Five UC San Diego Researchers Receive Presidential Early Career Awards

January 17, 2025

President Joseph R. Biden announced this week the recipients of the Presidential Early Career Award for Scientists and Engineers (PECASE), including five faculty members from the University of California San Diego. The PECASE is the highest honor bestowed by the United States government to scientists and engineers in the early stages of their independent research careers.

Scientists Unveil Surprising Human vs Mouse Differences in a Major Cancer Immunotherapy Target

January 3, 2025

Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, researchers have found that PD-1 in mice is significantly weaker than the human version, providing new information on how cancer treatments are developed.

Enzyme Promoting Tumor Growth and Spread in Pancreatic Cancer Identified

January 2, 2025

An enzyme called MICAL2 promotes tumor growth and metastasis in the most common form of pancreatic cancer, according to a new study by UC San Diego School of Medicine researchers.

Staphylococcus Aureus Thwarts Vaccines by Turning on a Protein That Halts Immune Response

December 16, 2024

After dozens of clinical trials, there are still no effective vaccines against Staphylococcus aureus. In two new studies, scientists report that the pathogen turns on the protein interleukin 10, shutting down the protective vaccine response. But blocking the protein restores vaccine efficacy in an animal model.

Kimberly Cooper and Elizabeth Villa Named Pew Innovation Fund Investigators

December 10, 2024

UC San Diego School of Biological Sciences Professors Kimberly Cooper and Elizabeth Villa have been selected by the Pew Charitable Trusts as members of its 2024 class of Innovation Fund Investigators.

Changes in Blood Cell Production Over the Lifetime Could Impact Leukemia Outcomes

December 5, 2024

The first comprehensive map of the dramatic changes that take place in the blood system over the course of the human lifetime could have implications for the treatment of acute myeloid leukemia and other blood diseases.

UC San Diego Ranks 9th in the World for Most Influential Researchers

November 26, 2024

UC San Diego has the highest number of influential voices in the University of California system and tied for 9th highest among universities and institutes worldwide, according to Clarivate’s 2024 Highly Cited Researchers list.

New Gene Drive Reverses Insecticide Resistance in Pests… Then Disappears

November 22, 2024

UC San Diego geneticists have developed a gene drive-based solution to the widespread problem of insecticide resistance. In an effort to protect valuable crops, the researchers created an “e-Drive” that reverses insecticide resistance and then disappears from the insect population.
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