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News Archive - Mario Aguilera

Yishi Jin Named to Junior Seau Endowed Faculty Chair in Traumatic Brain Injury

March 8, 2018

The inaugural chair holder of the Junior Seau Foundation Endowed Chair in Traumatic Brain Injury at the University of California San Diego is Yishi Jin, Professor and Chair of the Section of Neurobiology in the Division of Biological Sciences. Jin’s research focuses on molecular genetic mechanisms underlying the development of the nervous system, and regeneration of wounded nervous systems, with the goal of better understanding human neurological disorders and brain injury.

Yishi Jin Named to Junior Seau Endowed Faculty Chair in Traumatic Brain Injury

March 8, 2018

The inaugural chair holder of the Junior Seau Foundation Endowed Chair in Traumatic Brain Injury at the University of California San Diego is Yishi Jin, Professor and Chair of the Section of Neurobiology in the Division of Biological Sciences. Jin’s research focuses on molecular genetic mechanisms underlying the development of the nervous system, and regeneration of wounded nervous systems, with the goal of better understanding human neurological disorders and brain injury.

Surprise Finding Points to DNA’s Role in Shaping Cells

February 8, 2018

Working at the intersection of biology and physics, scientists at UC San Diego have made a surprising discovery at the root of cell formation. They found that DNA executes an unexpected architectural role in shaping the cells of bacteria. Studying the bacterium Bacillus subtilis, the researchers used an array of experiments and technologies to reveal that DNA, beyond serving to encode genetic information, also “pumps up” bacterial cells.

Active Genetics Technology Opens New Horizons

February 6, 2018

Employing CRISPR/Cas9 advancements, UC San Diego researchers are using new active genetics technology to reveal new fundamental mechanisms that control gene activity. The authors also provide experimental validation for using active genetics as an efficient means for targeted gene insertion, or “transgenesis,” and single-step replacement of genetic control elements.

Novel Technologies Reveal Key Information About Depleted East Pacific Green Sea Turtles

January 29, 2018

Using new technologies developed to extract life history information from bones, researchers at UC San Diego are learning more than ever about populations of green sea turtles living in the eastern region of the Pacific Ocean. While their numbers remain dangerously depleted, the new data show that green sea turtles are spending more time offshore, increasing their risk as fishing bycatch.

Discovery Offers New Genetic Pathway for Injured Nerve Regeneration

January 25, 2018

Researchers on the hunt for genes involved in regenerating critical nerve fibers came away with a surprise: The discovery of a new genetic pathway that carries hope for victims of traumatic injuries—from stroke to spinal cord damage. Although no cures exist for many nervous system injuries, if the damaged neurons do not die, “there is hope to find ways to make them stronger and help them regrow,” said senior author Yishi Jin.

Worldwide Importance of Honey Bees for Natural Habitats Captured in New Report

January 10, 2018

An unprecedented UC San Diego study integrating data from around the globe has shown that honey bees are the world’s most important single species of pollinator in natural ecosystems and a key contributor to natural ecosystem functions. The report weaves together information from 80 plant-pollinator interaction networks.

Pesticides and Poor Nutrition Damage Animal Health

December 19, 2017

The combined effects of pesticides and a lack of nutrition form a deadly one-two punch for animals, new research shows for the first time. Researchers studied how honey bees fared with exposure to pesticides and limited nutrient sources, scenarios found in agricultural areas. They were surprised to find that bee deaths increased by up to 50 percent more than they expected.

Scientists Identify Promising New Approach for Immune System Defense against Cancer

December 11, 2017

Researchers have identified a promising new strategy to fight infections and cancer. They uncovered a novel function for a protein known as “Runx3” that is key to the development of killer T cells—immune cells important for fighting infections and cancer. The researchers believe Runx3, if properly directed, could be combined with other approaches to help T cells recognize and destroy tumor cells and enhance vaccine efficacy.

‘SUMO’ Research at UC San Diego Wrestles with New Way to Read Cellular Function

November 21, 2017

University of California San Diego researchers in the Department of Chemistry and Biochemistry and in the Section of Cell and Developmental Biology have “got mail”—of the cellular sort. They know that cells have elaborate “addressing” functions that “send” proteins to the correct compartment, but they are now learning how cells “’write” the addresses and then “read” them. This is important because cellular function depends on each molecule in the cell being where it is supposed to be. But, often, protein molecules are not made in the compartment where they eventually need to function. In a paper recently published in Nature Communications, Professor Elizabeth Komives, chemistry and biochemisty, and Associate Professor Eric Bennett, cell and developmental biology, outline their research.
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