July 20, 2018
July 20, 2018 —
…of Medicine researchers investigating stem cell-based therapies for a rare genetic disorder that affects the heart and a chronic, progressive affliction of the lungs.
September 21, 2011
September 21, 2011 —
For the first time ever, a surgical team led by Alan Hemming, MD, has successfully performed a domino transplant using a liver with a rare genetic disorder called methylmalonic acidemia (MMA).
December 21, 2011
December 21, 2011 —
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, reports that abnormal sequences of DNA known as rare copy number variants, or CNVs, appear to play a significant role in the risk for early onset bipolar disorder.
April 13, 2023
April 13, 2023 —
UC San Diego researchers describe for the first time how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body’s ability to suppress it.
April 22, 2024
April 22, 2024 —
New research by scientists at University of California San Diego has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.
October 9, 2013
October 9, 2013 —
…of Medicine, says a gene mutation that causes a rare but devastating neurological disorder known as Lesch-Nyhan syndrome appears to offer clues to the developmental and neuronal defects found in other, diverse neurological disorders like Alzheimer’s, Parkinson’s and Huntington’s diseases.
April 16, 2018
April 16, 2018 —
The National Institute of Allergy and Infectious Diseases has awarded a five-year, $15 million grant to the San Diego Center for AIDS Research (CFAR) https://cfar.ucsd.edu at UC San Diego, renewing support that extends back to an original establishing grant in 1994—the height of the AIDS epidemic.
May 18, 2023
May 18, 2023 —
Biologists have used machine learning, a type of AI, to identify “synthetic extreme” DNA sequences with specifically designed functions in gene activation. They tested 50 million DNA sequences and found synthetic DNA sequences with activities that could be useful in biotechnology and medicine.
September 13, 2018
September 13, 2018 —
Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba’s growth in a laboratory dish. Several of these drugs are already approved…
March 18, 2020
March 18, 2020 —
New study finds gene therapy improved cardiac, muscle and liver function in Danon disease mouse models.