August 29, 2018
Over the next five years, the National Heart, Lung, and Blood Institute, part of the National Institutes of Health, will award approximately $20 million to four academic centers to launch a new national Career Development Consortium for Excellence in Glycosciences.
October 24, 2022
Using a novel systems biology approach, scientists at UC San Diego School of Medicine have further parsed the cellular players and roles involved in rheumatoid arthritis, a complex disease that affects more than one million Americans in ways that have defied development of uniform treatments.
March 13, 2012
Tracking the genetic pathway of a disease offers a powerful, new approach to drug discovery, according to scientists at the University of California, San Diego School of Medicine who used the approach to uncover a potential treatment for prostate cancer, using a drug currently marketed for congestive heart failure.
July 16, 2020
Scientists have unraveled key mechanisms behind the mysteries of aging. They isolated two paths that cells travel during aging and engineered a new way to genetically program these aging routes. The researchers also identified a master circuit that guides the aging processes.
March 17, 2020
UC San Diego researchers have developed a computational tool that makes modeling and simulation of complex cellular processes more true to life. The tool, dubbed GAMer 2, simplifies the process of using realistic cell geometries in mathematical models.
August 13, 2014
In a paper published online this week in Nature, researchers at the University of California, San Diego School of Medicine elaborate upon a crucial signaling pathway and the role of key proteins, which may help clear the way to generate HSCs from human pluripotent precursors, similar to advances with other…
November 14, 2011
…at developing therapies for heart failure and cardiac pacemaker dysfunction. To repair of human heart, it is important to study human cardiac progenitors and to define pathways required to grow and differentiate them utilizing human cells as a model experimental system. Evans’ lab will create special lines of human embryonic…
September 27, 2012
…resulting inflammation in the heart and blood vessels. Researchers at the University of California, San Diego School of Medicine, with colleagues at institutions across the country, say the relationship is not exactly what it appears, and that a precursor to cholesterol actually suppresses inflammatory response genes. This precursor molecule could…
August 19, 2024
A team of researchers from UC San Diego has developed the first multiscale computational model to simulate the therapeutic mechanisms of a drug candidate for heart failure from the atomic level to the organ system scale.
January 6, 2021
Biologists have unraveled the mystery of how chromosomes are inherited correctly every time a cell divides. They discovered how a “matchmaker” molecule stops cell division until components are ready to be split. Alterations in the process can result in birth defects and certain cancers.
