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Your search for “genetics” returned 1157 results

Controlling Cholesterol in Microglia Alleviates Chronic Pain, Opioid-Free

May 10, 2021

Using a mouse model, researchers discover pivotal role of cholesterol in chronic pain often caused by chemotherapy, and propose novel therapy.

Superficial Relationship: Enzymes Protect the Skin by Ignoring Microbes and Viruses

May 21, 2021

UC San Diego School of Medicine researchers identify how the body regulates and prevents constant skin inflammation.

UC San Diego Health Begins Treating Multiple Myeloma with CAR T-cell Therapy

June 3, 2021

As the first designated medical center in San Diego certified to offer this type of immunotherapy, UC San Diego Health will begin treating patients this month.

Potential Drug Target for Difficult-To-Treat Breast Cancer: RNA-Binding Proteins

July 2, 2021

UC San Diego studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers.

Artificial Intelligence Could Be New Blueprint for Precision Drug Discovery

July 12, 2021

Researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

Ultrasound Remotely Triggers Immune Cells to Attack Tumors in Mice Without Toxic Side Effects

August 12, 2021

A new cancer immunotherapy pairs ultrasound with cancer-killing immune cells to destroy malignant tumors while sparing normal tissue. The approach could make chimeric antigen receptor (CAR) T-cell therapy safer and effective at treating solid tumors.

A Target for Potential Cancer Drugs May, In Fact, Worsen Disease

November 9, 2021

Researchers reveal a previously unrealized complexity in cancer development, one that raises concerns and caution about targeting an enzyme popular in oncological treatments.

State Stem Cell Agency Awards $4M for Blood Cancer Immunotherapy at UC San Diego

November 24, 2021

The California Institute for Regenerative Medicine (CIRM) approved a $4.1 million grant to enable University of California San Diego School of Medicine researchers to advance a new chimeric antigen receptor (CAR) T-cell therapy from the laboratory into the clinic.

Nuclei-free Cells Prove Utility in Delivering Therapeutics to Diseased Tissues

January 14, 2022

UC San Diego researchers report successfully removing the nucleus from a type of ubiquitous cell, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues.Researchers at University of California San Diego School of Medicine and Moores

Alcohol Use Linked to Lower Connectivity in Brain Areas that Process Emotions

February 8, 2022

People at risk of developing alcohol use disorder show lower functional connectivity between brain regions involved in processing facial expressions. Future psychoeducation programs focused on improving social and emotional processing may help prevent alcohol use disorder.

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