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Your search for “genetics” returned 1166 results

Controlling CAR T Cells with Light Selectively Destroys Skin Tumors in Mice

February 19, 2020

UC San Diego bioengineers developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed to blue light, the researchers controlled the cells to destroy skin tumors in mice without harming healthy tissue

Gut Microbes Influence How Rat Brains React to Opioids

April 27, 2020

Antibiotic treatment — which depletes gut microbes — drastically changes the parts of a rat’s brain that are activated during opioid addiction and withdrawal.

Implanted Neural Stem Cell Grafts Show Functionality in Spinal Cord Injuries

August 5, 2020

Researchers at UC San Diego School of Medicine report successfully implanting specialized grafts of neural stem cells directly into spinal cord injuries in mice, then documenting how the grafts grew and filled the injury sites, mimicking the animals’ existing neuronal network.

How SARS-CoV-2 Went from Single Cases to Overwhelming Continents

September 16, 2020

Early detection and intervention stanched the first known introductions of the SARS-CoV-2 virus into North America and Europe, validating the effectiveness of quick, comprehensive testing and contact tracing, but inadequate public health measures allowed the virus to take hold.

Scientists Set a Path for Field Trials of Gene Drive Organisms

December 17, 2020

A broad coalition that includes UC San Diego scientists sets commitments for field trials of powerful gene drive technology. The multidisciplinary group encourages trials that are safe, transparent and ethical.

Scientists Developing New Solutions for Honeybee Colony Collapse

January 8, 2021

Under a new effort to halt a worldwide decline in honeybees, scientists at UC San Diego and other UC campuses have established a network of bee researchers and engineers. The network, one of the largest in the country, will develop new solutions by joining various avenues of expertise.

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

February 18, 2021

UC San Diego researchers have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease or Mild Cognitive Impairment, a condition that often precedes full-blown dementia.

Gene Therapy in Alzheimer’s Disease Mouse Model Preserves Learning and Memory

May 4, 2021

Researchers at UC San Diego have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer’s disease, a key step toward eventually testing the approach in humans with the neurodegenerative disease.

Controlling Cholesterol in Microglia Alleviates Chronic Pain, Opioid-Free

May 10, 2021

Using a mouse model, researchers discover pivotal role of cholesterol in chronic pain often caused by chemotherapy, and propose novel therapy.

Superficial Relationship: Enzymes Protect the Skin by Ignoring Microbes and Viruses

May 21, 2021

UC San Diego School of Medicine researchers identify how the body regulates and prevents constant skin inflammation.

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