October 26, 2017
Scientists have known that areas of the brain with similar functions—even those in different brain hemispheres—connect to share signals when the body rests, but they haven’t known how this “resting-state connectivity” occurs. Now, scientists in the Neurophysics Laboratory at the University of California San Diego may have the answer.
December 11, 2017
Rare stem-like tumor cells play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these cells using existing drugs before metastatic disease occurs, report University of California San Diego School of Medicine and Moores Cancer Center…
June 29, 2018
Emerging CAR-T immunotherapies leverage modified versions of patient’s T-cells to target and kill cancer cells. In a new study, researchers at University of California San Diego School of Medicine and University of Minnesota report that similarly modified natural killer (NK) cells derived from human induced pluripotent stem cells (iPSCs) also…
August 22, 2018
An international team of researchers has uncovered a destructive mechanism at the molecular level that causes a well-known phenomenon associated with obesity, called leptin resistance. They found that mice fed a high-fat diet produce an enzyme named MMP-2 that clips receptors for the hormone leptin from the surface of neuronal…
November 12, 2018
Researchers at University of California San Diego School of Medicine, Scripps Institution of Oceanography, and international collaborators have evidence that Kawasaki Disease (KD) does not have a single cause. By studying weather patterns and geographical distributions of patients in San Diego, the research team determined that this inflammatory disease likely…
December 3, 2018
Following the FDA’s approval of chimeric antigen receptor (CAR) T-cell therapies for the treatment of certain types of non-Hodgkin lymphomas, UC San Diego Health was the first medical center in San Diego to be certified to offer this type of immunotherapy outside of a clinical trial.
June 17, 2019
Two UC San Diego undergraduate students were named Donald A. Strauss Foundation Public Service Scholars, and were awarded a $15,000 prize to pursue their social change and public service projects.
September 23, 2019
When we eat red meat, the animal carbohydrate Neu5Gc is incorporated in our tissues, where it generates inflammation. UC San Diego researchers discovered how gut bacteria enzymes strip our cells of Neu5Gc, introducing the possibility of using the enzymes to reduce the risk of inflammatory diseases.
October 15, 2019
UC San Diego bioengineers are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR T cells get turned on so that they destroy cancer cells without harming normal cells.
December 9, 2019
Scientists have found the most effective CRISPR shield ever discovered in viruses. They discovered a remarkable new strategy that some bacteria-killing viruses, or phages, employ: after they infect bacteria, these phages construct an impenetrable “safe room” inside of their host.
