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Your search for “gene therapy” returned 703 results

Alternative Proteins Encoded by Same Gene Have Widely Divergent Functions

February 11, 2016

A single human gene can produce many different proteins. In the first large-scale study of its kind, researchers at University of California, San Diego School of Medicine, Dana-Farber Cancer Institute and McGill University report that most of these sibling proteins encoded by the same gene — known as protein isoforms…

Tethering of Shattered Chromosomal Fragments Paves Way for New Cancer Therapies

June 15, 2023

UC San Diego scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations

New Research Helps Explain the Genetic Basis of Why We Look the Way We Do

November 10, 2021

Comparing features of a common laboratory fruit fly with its rarer cousin collected from Hawai’i Volcanoes National Park, UC San Diego researchers used CRISPR technology to uncover clues about how high-level control genes called Hox genes shape our appearance.

Non-Coding DNA Located Outside Chromosomes May Help Drive Glioblastoma

November 21, 2019

According to a new Cell study, extra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going — elements that could represent new drug targets for brain tumors and other cancers notoriously difficult to treat.

New Biomarker Identified in Women with Mental Illness

June 19, 2015

…report identifying a biological marker: the over-production of specific genes that could be a diagnostic indicator of mental illness in female psychiatric patients.

With Gene Therapy, Scientists Develop Opioid-Free Solution for Chronic Pain

March 10, 2021

A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. By temporarily repressing a gene involved in sensing pain, the treatment increased pain tolerance in mice, lowered their sensitivity to pain and provided months of pain relief without causing numbness.

New Reprogramming Method Makes Better Stem Cells

July 2, 2014

…cells and could ultimately lead to improved stem cell therapies.

Genomic Study Revealing Among Diverse Populations with Inherited Retinal Disease

October 19, 2021

An international team of researchers has broadened and deepened understanding of how inherited retinal dystrophies (IRDs) affect different populations of people and, in the process, have identified new gene variants that may cause the diseases.

Altered Cell Cycle Gene Activity Underlies Brain Overgrowth in Autistic Toddlers

December 14, 2015

Further underscoring the prenatal origins of Autism Spectrum Disorder (ASD), researchers at University of California, San Diego School of Medicine describe for the first time how abnormal gene activity in cell cycle networks that are known to control brain cell production may underlie abnormal early brain growth in the disorder.

Gene Mutation Found for Aggressive Form of Pancreatic Cancer

May 25, 2014

Researchers at the University of California, San Diego School of Medicine have identified a mutated gene common to adenosquamous carcinoma (ASC) tumors – the first known unique molecular signature for this rare, but particularly virulent, form of pancreatic cancer.

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