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Your search for “drug development” returned 976 results

UC San Diego Biologists Produce Rainbow-Colored Algae

March 7, 2013

What can green algae do for science if they weren’t, well, green? That’s the question biologists at UC San Diego sought to answer when they engineered a green alga used commonly in laboratories, Chlamydomonas reinhardtii, into a rainbow of different colors by producing six different colored fluorescent proteins in the…

DrugCell: New Experimental AI Platform Matches Tumor to Best Drug Combo

October 22, 2020

UC San Diego researchers use experimental artificial intelligence system called DrugCell to predict the best approach to treating cancer. Only 4 percent of all cancer therapeutic drugs under development earn final approval by the U.S. Food and Drug Administration (FDA).

New Tool Assesses Evolutionary Risks of Antibiotics

January 18, 2022

Countering a rising antibiotic resistance crisis, doctors now prescribe combinations of antibiotics. Yet many risks are involved with such multi-drug combinations. Scientists have developed a way to help doctors evaluate outcomes for different drug pairs and boost the odds of successful treatment.

UC San Diego Receives Grand Challenges Explorations Grant For Cutting-edge Research in Global Health

May 21, 2013

…Training Program will pursue an innovative global health and development research project, titled “Outsmarting Malaria: Developing next generation anti-malarials that prevent the evolution of drug resistance.”

New Tool Allows Scientists to Visualize ‘Nanoscale’ Processes

May 3, 2016

Chemists at UC San Diego have developed a new tool that allows scientists for the first time to see, at the scale of five billionths of a meter, “nanoscale” mixing processes occurring in liquids.

Researchers Unveil New Approach to Flip the Script on Drug Addiction

February 1, 2024

UC San Diego scientists are working to flip the script on drug addiction with a $1.3 million grant from the W.M. Keck Foundation. Their new approach, called negative feedback chemogenetics, works by leveraging the body’s biochemical feedback processes to disrupt pathways associated with addiction.

Discovery Provides Blueprint for New Drugs That Can Inhibit Hepatitis C Virus

March 19, 2012

Chemists at the University of California, San Diego have produced the first high resolution structure of a molecule that when attached to the genetic material of the hepatitis C virus prevents it from reproducing. Hepatitis C is a chronic infectious disease that affects some 170 million people worldwide and causes…

Supercomputers Simulate New Pathways for Potential RNA Virus Treatment

December 17, 2020

New simulations done on supercomputers may help researchers understand how these inhibitors react and potentially help to develop a new generation of drugs to target viruses with high death rates including SARS-CoV2, the virus that causes COVID-19.

A Pediatric Cancer Drug Three Decades in the Making

October 8, 2015

…Ph.D. A Pediatric Cancer Drug Three Decades in the Making By the age of 4, Matthew Haemsch had undergone 16 rounds of chemotherapy and a surgery to remove a cancerous tumor on his adrenal gland. Yet, his small body remained riddled with a rare pediatric cancer. With no other treatment…

Gene Editing Technique Helps Find Cancer’s Weak Spots

March 20, 2017

…cells, allowing researchers to develop drugs that will selectively kill them. This is called “synthetic lethality” because the drug is only lethal to mutated (synthetic) cells. Researchers at UC San Diego School of Medicine and Jacobs School of Engineering developed a method to search for synthetic-lethal gene combinations. The technique,…

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