October 26, 2022
Researchers at UC San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs. The discovery opens the possibility of new therapies, including for multiple forms of cancer.
December 7, 2018
David Cheresh, Distinguished Professor at University of California San Diego School of Medicine, received $4.2 million National Cancer Institute Outstanding Investigator Award to continue his research into cancer’s ability to overcome stress, gain drug resistance and metastasize.
March 7, 2013
What can green algae do for science if they weren’t, well, green? That’s the question biologists at UC San Diego sought to answer when they engineered a green alga used commonly in laboratories, Chlamydomonas reinhardtii, into a rainbow of different colors by producing six different colored fluorescent proteins in the…
October 22, 2020
UC San Diego researchers use experimental artificial intelligence system called DrugCell to predict the best approach to treating cancer. Only 4 percent of all cancer therapeutic drugs under development earn final approval by the U.S. Food and Drug Administration (FDA).
January 18, 2022
Countering a rising antibiotic resistance crisis, doctors now prescribe combinations of antibiotics. Yet many risks are involved with such multi-drug combinations. Scientists have developed a way to help doctors evaluate outcomes for different drug pairs and boost the odds of successful treatment.
May 21, 2013
…Training Program will pursue an innovative global health and development research project, titled “Outsmarting Malaria: Developing next generation anti-malarials that prevent the evolution of drug resistance.”
May 3, 2016
Chemists at UC San Diego have developed a new tool that allows scientists for the first time to see, at the scale of five billionths of a meter, “nanoscale” mixing processes occurring in liquids.
March 19, 2012
Chemists at the University of California, San Diego have produced the first high resolution structure of a molecule that when attached to the genetic material of the hepatitis C virus prevents it from reproducing. Hepatitis C is a chronic infectious disease that affects some 170 million people worldwide and causes…
October 8, 2015
…Ph.D. A Pediatric Cancer Drug Three Decades in the Making By the age of 4, Matthew Haemsch had undergone 16 rounds of chemotherapy and a surgery to remove a cancerous tumor on his adrenal gland. Yet, his small body remained riddled with a rare pediatric cancer. With no other treatment…
March 20, 2017
…cells, allowing researchers to develop drugs that will selectively kill them. This is called “synthetic lethality” because the drug is only lethal to mutated (synthetic) cells. Researchers at UC San Diego School of Medicine and Jacobs School of Engineering developed a method to search for synthetic-lethal gene combinations. The technique,…
