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Your search for “brain organoids” returned 53 results

Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids

May 2, 2022

UC San Diego scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function.

Brain Organoids Mimic Head Size Changes Associated with Type of Autism

August 25, 2021

Stem cell models derived from people with specific genomic variation recapitulate aspects of their autism spectrum disorder, providing a valuable model to study the condition and look for therapeutic interventions.

Building Mini-Brains to Study Disorders Caused by HIV and Meth Use

February 10, 2015

…involving the creation of miniature models of the human brain – developed with stem cells – to study neurological disorders caused by HIV and methamphetamine use has been named one of five recipients of the 2015 Avant-Garde Award for HIV/AIDS Research from the National Institute on Drug Abuse (NIDA).

Human Gut-in-a-Dish Model Helps Define ‘Leaky Gut,’ and Outline a Pathway to Treatment

February 10, 2020

UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.

Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models

May 11, 2016

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first “direct experimental proof” that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature.

Inflamed Support Cells Appear to Contribute to Some Kinds of Autism

October 18, 2017

Modeling the interplay between neurons and astrocytes derived from children with Autism Spectrum Disorder (ASD), researchers at University of California San Diego School of Medicine, with colleagues in Brazil, say innate inflammation in the latter appears to contribute to neuronal dysfunction in at least some forms of the disease.

$12.7M Grant to Establish New Center to Investigate Genetic Basis of Autism and Schizophrenia

October 10, 2024

Funded by a California Institute for Regenerative Medicine grant, researchers in the UC San Diego Verge Center aim to uncover the genetic mechanisms behind neuropsychiatric disorders.

UC San Diego to Advance Stem Cell Therapies in New Space Station Lab

April 8, 2020

UC San Diego and Space Tango received a NASA award to develop the first dedicated stem cell research laboratory within the International Space Station.

Organoids Reveal How SARS-CoV-2 Damages Brain Cells — and a Potential Treatment

November 3, 2022

Using human brain organoids, an international team of researchers has shown how the SARS-CoV-2 virus that causes COVID-19 infects cortical neurons and specifically destroys their synapses — the connections between brain cells that allow them to communicate with each other.

UC San Diego Receives $1.3M from W. M. Keck Foundation to Study Origins of Dementia

August 16, 2022

Researchers at the University of California San Diego have received a $1.3 million grant from the W.M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective

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