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Your search for “brain organoids” returned 49 results

Human Brain Organoids Implanted into Mouse Cortex Respond to Visual Stimuli for First Time

December 28, 2022

A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals’ cortex and responded to external sensory stimuli.

Building a Better Brain-in-a-Dish, Faster and Cheaper

September 6, 2018

Writing in the current online issue of the journal Stem Cells and Development, researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.

Zika Virus May Cause Microcephaly by Hijacking Human Immune Molecule

May 6, 2016

…determined one way Zika virus infection can damage developing brain cells. The study, published May 6 in Cell Stem Cell, also shows that inhibiting this mechanism reduces brain cell damage, hinting at a new therapeutic approach to mitigating the effects of prenatal Zika virus infection.

2019: A Space Organoid

July 8, 2019

UC San Diego will launch a payload of stem cell-derived human brain organoids to the International Space Station. Researchers will document how these “mini brains” organize into the beginnings of a functional brain with implications for the future of human life in space.

Machine Learning Algorithm Can’t Distinguish These Lab Mini-Brains from Preemie Babies

August 29, 2019

Nine-month-old brains-in-a-dish and the brains of premature newborn babies generate similar electrical patterns, as captured by electroencephalogram (EEG) — the first time such brain activity has been achieved in a cell-based laboratory model.

Brain Organoids Reveal in Detail the Harms of Prenatal Alcohol Exposure

November 18, 2022

UC San Diego researchers used human brain organoids to study the effects of prenatal alcohol exposure on neural development, revealing significant harms in molecular detail.

Human Lung and Brain Organoids Respond Differently to SARS-CoV-2 Infection in Lab Tests

February 24, 2021

UC San Diego School of Medicine researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies.

Lab-Grown Human Brain Organoids Mimic an Autism Spectrum Disorder, Help Test Treatments

December 8, 2020

UC San Diego researchers used brain organoids to identify two drug candidates that counteract the genetic deficiencies that cause Rett syndrome, a rare form of autism spectrum disorder.

How a Single Gene Alteration May Have Separated Modern Humans from Predecessors

February 11, 2021

UC San Diego researchers discovered a single gene alteration that may help explain cognitive differences between modern humans and our predecessor, and used that information to develop Neanderthal-like brain organoids in the lab.

Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids

May 2, 2022

UC San Diego scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function.

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