Familiarity Breeds Exempt: Why Staph Vaccines Don’t Work in Humans
July 7, 2022
UC San Diego researchers say they may have found the reason why multiple human clinical trials of staphylococcus vaccines have failed: the bacteria knows us too well.
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Targeting Molecular Pathway that Causes Pulmonary Arterial Hypertension
May 6, 2022
UC San Diego researchers describe the underlying signaling pathway that results in pulmonary arterial hypertension and a novel monoclonal antibody therapy that blocks the abnormal blood vessel formation characterizing the disease.
Novel Approaches to Treating Alzheimer’s Disease Include Early Intervention
May 15, 2012
Researchers at the Comprehensive Alzheimer’s Program at the University of California, San Diego School of Medicine have announced two new clinical trials for patients with either mild to moderate Alzheimer’s disease (AD) and one trial for Mild Cognitive Impairment.
Biologists Create Malaria-Blocking Mosquitoes
November 23, 2015
Using a groundbreaking gene editing technique, biologists at UC San Diego, working in collaboration with biologists at UC Irvine, have created a strain of mosquitoes capable of rapidly introducing malaria-blocking genes into a mosquito population through its progeny, ultimately eliminating the insects’ ability to transmit the disease to humans.
Protein-Protein Interaction Activates and Fuels Leukemia Cell Growth
December 21, 2015
Building upon previous research, scientists at University of California, San Diego School of Medicine and UC San Diego Moores Cancer report that a protein called Wnt5a acts on a pair of tumor-surface proteins, called ROR1 and ROR2, to accelerate the proliferation and spread of chronic lymphocytic leukemia (CLL) cells, the…
Repurposed Arthritis Drug Did Not Significantly Improve Severe COVID-19 Pneumonia
March 1, 2021
A repurposed drug used to treat arthritis did not significantly improve the outcomes of patients with severe COVID-19 pneumonia. Tocilizumab did not significantly improve clinical status or mortality rate at 28 days for participants who received it compared to a placebo.
A Novel COVID-19 Vaccine Using Modified Bacterial DNA
July 21, 2022
UC San Diego researchers describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new and emerging variants and could be taken as a pill, by inhalation or other delivery methods.
Transplant, Cancer Patients Among First to Get Evusheld at UC San Diego Health
March 21, 2022
UC San Diego Health is now administering Evusheld to eligible, immunocompromised patients to protect against the COVID-19 virus.
UC San Diego Health Performs Region’s First Heart-Liver Transplant
November 30, 2016
On November 4, 2016, surgeons at UC San Diego Health performed the region’s first combined heart-liver transplant (CHLT). During the 10-hour surgery, 54-year old Frank “Sonny” Taitano received a healthy heart and liver. This is the first successful heart-liver transplant for San Diego; less than 10 of these surgeries are…
UC San Diego Researcher to Study Most Effective Treatment for Kawasaki Disease
February 2, 2017
Researchers at University of California San Diego School of Medicine, Rady Children’s Hospital-San Diego and Betty Irene Moore School of Nursing at University of California Davis have received a $2 million grant from the Patient-Centered Outcomes Research Institute (PCORI) for a three-year study to look at the effectiveness of two…
