March 8, 2018
March 8, 2018 —
…and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). The findings, they say, represent an important proof-of-concept for the compound as there are currently no Food and Drug Administration-approved treatments for NAFLD and NASH.
September 13, 2018
September 13, 2018 —
…caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2’s critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH — and possibly even reverse early…
November 1, 2018
November 1, 2018 —
…months or more are at lower risk for developing non-alcoholic fatty liver disease (NAFLD) years later during mid-life. With no other current prevention options aside from a healthy lifestyle, they say the finding may represent an early modifiable risk factor for a serious and chronic disease.
January 22, 2019
January 22, 2019 —
Researchers at University of California San Diego School of Medicine found that a diet low in free sugars (those added to foods and beverages and occurring naturally in fruit juices) resulted in significant improvement in nonalcoholic fatty liver disease (NAFLD) in adolescent boys.
August 24, 2020
August 24, 2020 —
Researchers at University of California San Diego School of Medicine report that fructose only adversely affects the liver after it reaches the intestines, where the sugar disrupts the epithelial barrier protecting internal organs from bacterial toxins in the gut.
November 23, 2020
November 23, 2020 —
Triclosan, an antimicrobial found in many soaps and other household items, worsens fatty liver disease in mice fed a high-fat diet.
July 12, 2021
July 12, 2021 —
Researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.
August 4, 2022
August 4, 2022 —
UC San Diego researchers report using native bacteria in mice as the chassis for delivering transgenes capable of inducing persistent and potentially even curative therapeutic changes in the gut and reversing disease pathologies.
December 4, 2023
December 4, 2023 —
UC San Diego has the highest number of influential voices in the University of California system and ranks 7th highest among universities worldwide, according to Clarivate’s 2023 Highly Cited Researchers list.
June 7, 2023
June 7, 2023 —
A new UC San Diego study published in JAMA Network Open provides an early look into how artificially intelligent assistants could help answer public health questions.