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Your search for “organoids” returned 67 results

Novel Stem Cell-Derived Model Created of Inflammatory Neurological Disorder

August 10, 2017

An international team of scientists, led by University of California San Diego School of Medicine researchers, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS). In doing so, the team was able to identify unusual and surprising underlying genetic…

Appendiceal Cancer Gets Its Own Preclinical Model

November 1, 2022

Researchers at UC San Diego School of Medicine and Moores Cancer Center at UC San Diego Health describe the first preclinical model of appendiceal cancer that contains all elements of the tumor, allowing previously stymied investigations to proceed.

Super Productive 3D Bioprinter Could Help Speed Up Drug Development

June 8, 2021

A new 3D bioprinter developed by UC San Diego nanoengineers operates at record speed—it can print a 96-well array of living human tissue samples within 30 minutes. The technology could help accelerate high-throughput preclinical drug screening and make it less costly.

Scientists Receive $4.8M to Pursue Gene Therapy for ‘Incurable’ Disease

December 1, 2022

The California Institute for Regenerative Medicine has awarded UC San Diego researchers $4.8 million to advance a gene therapy to treat Friedreich’s ataxia, a rare but devastating neuromuscular disorder.

Cancer Drug Could Ease Cognitive Function for Some With Autism

July 25, 2024

An experimental cancer drug could ease cognition for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the Muotri Lab at the University of California San Diego — a discovery that could lead to therapies for patients with other neurologic conditions.

New Drug Screening Method Answers Why Alzheimer’s Drugs Fail, Suggests New Targets

January 27, 2022

A study led by UC San Diego sheds light on why Alzheimer’s drugs so far have been ineffective at curing or reversing the disease. The researchers identify new targets for drug development and present a new method to screen drugs for treating Alzheimer’s disease.

One-Two Punch: Novel Drug Pairing Could Beat Pancreatic Cancer

June 28, 2023

UC San Diego researchers find a combination of drugs outperformed other treatments in human and mouse models of pancreatic cancer; now urge clinical trial

Post-COVID Lung Disease Shares Origins with Other Scarring Lung Disorders

July 20, 2022

UC San Diego researchers provide first insights into the fundamental cellular pathologies that drive interstitial lung disease in patients post-COVID.

‘Pop-up’ Electronic Sensors Could Detect When Individual Heart Cells Misbehave

December 23, 2021

UC San Diego engineers developed a powerful new tool that directly measures the movement and speed of electrical signals inside heart cells, using tiny “pop-up” sensors that poke into cells without damaging them. It could be used to gain more detailed insights into heart disorders and diseases.

UC San Diego Researchers Named Recipients of NIH New Innovator Awards

October 18, 2022

Two early career researchers at the University of California San Diego have been named recipients of the 2022 National Institutes of Health (NIH) Director’s New Innovator Award from the NIH Common Fund’s High-Risk, High-Reward Research program.

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