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Your search for “organoids” returned 58 results

Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids

May 2, 2022

UC San Diego scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function.

Lab-Grown Human Brain Organoids Mimic an Autism Spectrum Disorder, Help Test Treatments

December 8, 2020

UC San Diego researchers used brain organoids to identify two drug candidates that counteract the genetic deficiencies that cause Rett syndrome, a rare form of autism spectrum disorder.

How a Single Gene Alteration May Have Separated Modern Humans from Predecessors

February 11, 2021

UC San Diego researchers discovered a single gene alteration that may help explain cognitive differences between modern humans and our predecessor, and used that information to develop Neanderthal-like brain organoids in the lab.

Human Mini-Lungs Grown in Lab Dishes are Closest Yet to Real Thing

August 31, 2021

UC San Diego researchers developed first-of-their-kind lung organoids that include all cell types that make up the organ, allowing for “Phase 0” testing of new treatments for respiratory infections such as COVID-19.

Organoids Reveal How SARS-CoV-2 Damages Brain Cells — and a Potential Treatment

November 3, 2022

Using human brain organoids, an international team of researchers has shown how the SARS-CoV-2 virus that causes COVID-19 infects cortical neurons and specifically destroys their synapses — the connections between brain cells that allow them to communicate with each other.

Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models

May 11, 2016

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first “direct experimental proof” that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature.

Organoids Reveal Similarities Between Myotonic Dystrophy Type 1 and Rett Syndrome

June 29, 2022

Using brain organoids, UC San Diego researchers discover mutational commonalities between muscular dystrophy type 1 and Rett syndrome, suggesting the potential of a similar treatment for both.

Two UC San Diego Researchers Receive NIH High-Risk, High-Reward Awards

October 6, 2020

Two University of California San Diego researchers have received prestigious awards through the 2020 National Institutes of Health (NIH) High-Risk, High-Reward Research Program.

UC San Diego First to Test Cancer Drugs in Space Using Private Astronaut Mission

May 22, 2023

The latest space experiments from UC San Diego and Axiom Space will explore therapies for breast and colorectal cancer aboard the ISS, and monitor astronauts’ stem cell health over time.

UC San Diego to Advance Stem Cell Therapies in New Space Station Lab

April 8, 2020

UC San Diego and Space Tango received a NASA award to develop the first dedicated stem cell research laboratory within the International Space Station.

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