December 28, 2022
A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals’ cortex and responded to external sensory stimuli.
May 6, 2016
For the first time, researchers at University of California San Diego School of Medicine have determined one way Zika virus infection can damage developing brain cells. The study, published May 6 in Cell Stem Cell, also shows that inhibiting this mechanism reduces brain cell damage, hinting at a new therapeutic…
September 6, 2018
Writing in the current online issue of the journal Stem Cells and Development, researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.
February 24, 2021
UC San Diego School of Medicine researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies.
July 8, 2019
UC San Diego will launch a payload of stem cell-derived human brain organoids to the International Space Station. Researchers will document how these “mini brains” organize into the beginnings of a functional brain with implications for the future of human life in space.
November 18, 2022
UC San Diego researchers used human brain organoids to study the effects of prenatal alcohol exposure on neural development, revealing significant harms in molecular detail.
August 13, 2019
UC San Diego School of Medicine has been awarded $9 million to fund research projects using human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the cellular actions leading to disease onset.
February 10, 2020
UC San Diego researchers use 3D human gut organoids to reveal the molecular system that keeps intestinal linings sealed, demonstrate how the system breaks down and how it can be strengthened with the diabetes drug metformin.
August 25, 2021
Stem cell models derived from people with specific genomic variation recapitulate aspects of their autism spectrum disorder, providing a valuable model to study the condition and look for therapeutic interventions.
August 29, 2019
Nine-month-old brains-in-a-dish and the brains of premature newborn babies generate similar electrical patterns, as captured by electroencephalogram (EEG) — the first time such brain activity has been achieved in a cell-based laboratory model.
