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Your search for “organoids” returned 66 results

Human Brain Organoids Implanted into Mouse Cortex Respond to Visual Stimuli for First Time

December 28, 2022

A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals’ cortex and responded to external sensory stimuli.

Zika Virus May Cause Microcephaly by Hijacking Human Immune Molecule

May 6, 2016

For the first time, researchers at University of California San Diego School of Medicine have determined one way Zika virus infection can damage developing brain cells. The study, published May 6 in Cell Stem Cell, also shows that inhibiting this mechanism reduces brain cell damage, hinting at a new therapeutic…

Building a Better Brain-in-a-Dish, Faster and Cheaper

September 6, 2018

Writing in the current online issue of the journal Stem Cells and Development, researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.

Human Lung and Brain Organoids Respond Differently to SARS-CoV-2 Infection in Lab Tests

February 24, 2021

UC San Diego School of Medicine researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies.

Brain Organoids Reveal in Detail the Harms of Prenatal Alcohol Exposure

November 18, 2022

UC San Diego researchers used human brain organoids to study the effects of prenatal alcohol exposure on neural development, revealing significant harms in molecular detail.

UC San Diego Receives $9 Million in Grants to Pinpoint Cellular Cause of Type 1 Diabetes

August 13, 2019

UC San Diego School of Medicine has been awarded $9 million to fund research projects using human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the cellular actions leading to disease onset.

Brain Organoids Mimic Head Size Changes Associated with Type of Autism

August 25, 2021

Stem cell models derived from people with specific genomic variation recapitulate aspects of their autism spectrum disorder, providing a valuable model to study the condition and look for therapeutic interventions.

2019: A Space Organoid

July 8, 2019

UC San Diego will launch a payload of stem cell-derived human brain organoids to the International Space Station. Researchers will document how these “mini brains” organize into the beginnings of a functional brain with implications for the future of human life in space.

Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids

May 2, 2022

UC San Diego scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function.

Human Mini-Lungs Grown in Lab Dishes are Closest Yet to Real Thing

August 31, 2021

UC San Diego researchers developed first-of-their-kind lung organoids that include all cell types that make up the organ, allowing for “Phase 0” testing of new treatments for respiratory infections such as COVID-19.

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