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Your search for “Targeted Drug Delivery” returned 72 results

Nanoparticles Made From Plant Viruses Could Be Farmers’ New Ally in Pest Control

September 21, 2023

UC San Diego engineers have devised a new solution to control a major agricultural menace, root-damaging nematodes. Using plant viruses, they created nanoparticles that can deliver pesticides to previously unreachable soil depths. This could potentially minimize environmental toxicity and costs.

Synthetic Biology Used to Limit Bacterial Growth and Coordinate Drug Release

July 20, 2016

…team engineered a clinically relevant bacterium to produce cancer drugs and then self-destruct and release the drugs at the site of tumors. The approach enables continual production and release of drugs at disease sites in mice while simultaneously limiting the size, over time, of the populations of bacteria engineered to…

New Polymeric Material Developed at UC San Diego Has Potential for Use in Non-Invasive Surgical Proc

October 3, 2011

Scientists at the University of California, San Diego have developed what they believe to be the first polymeric material that is sensitive to biologically benign levels of near infrared (NRI) irradiation, enabling the material to disassemble in a highly controlled fashion.

UC San Diego and GSK Collaborate to Eradicate Cancer Stem Cells, Treat Leukemia

July 8, 2015

…(DPAc) program, where academic partners become core members of drug-hunting teams. Catriona Jamieson, MD, PhD, associate professor of medicine and chief of the Division of Regenerative Medicine, will lead UC San Diego’s effort in the new DPAc team.

New CRISPR-based Gene-Drive System in Bacteria Defeats Antibiotic Resistance

December 16, 2019

Scientists have developed a CRISPR-based gene-drive system that inactivates a gene rendering bacteria antibiotic-resistant. The new system leverages technology developed by UC San Diego biologists in insects and mammals that biases genetic inheritance of preferred traits called “active genetics.”

Scientists Race to Outpace Lethal Bacterial Infections

May 30, 2018

…between new antibiotics and drug-resistant bacteria—and scientists are challenged to keep up. By 2050, according to a Wellcome Trust study, deaths from deadly infections will be more common than cancer deaths. Scientists report that currently antimicrobial resistance causes 23,000 deaths annually in the U.S.; 700,000 deaths worldwide. Better methods to…

New Cages to Trap Molecules Push Boundaries of Protein Design

January 22, 2020

New research findings, published in Nature, by UC San Diego Professor of Chemistry and Biochemistry Akif Tezcan offer a protein architecture that pushes the boundaries of synthetic protein design past what is considered state-of-the-art.

Live and Let-7: MicroRNA Plays Surprising Role in Cell Survival

October 7, 2014

…cellular processes and may be key to developing new drugs and therapies.

International Consortium Builds ‘Google Map’ of Human Metabolism

March 4, 2013

Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction of human metabolism to date. Scientists could use the model, known as Recon 2, to identify causes of and new treatments for diseases…

Researchers Find a New Way to Identify and Target Malignant Aging in Leukemia

August 26, 2016

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already…

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