October 30, 2023
UC San Diego engineers have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins. The nanoparticles can be tailored for various applications, ranging from targeted drug delivery to neutralizing biological agents.
July 1, 2022
Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.
June 16, 2021
Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they’re needed.
February 10, 2022
New research led by bioengineers at the University of California San Diego could make it much simpler to repair disease-causing mutations in RNA without compromising precision or efficiency. The new RNA editing technology holds promise as a gene therapy for treating genetic diseases.
September 27, 2018
Scientists have known that bacteria produce small spherical versions of themselves. Lacking basic materials to reproduce or function like normal cells, the natural role of minicells—which protrude like budding balloons off the ends of bacteria—has remained a mystery. Now, researchers at UC San Diego have demonstrated for the first time…
September 16, 2015
…and systemic bacterial infections. These nanoparticles are capable of delivering drugs to targeted sites in the body — particularly injured blood vessels and organs infected by harmful bacteria. This targeted drug delivery greatly increased the therapeutic effects of drugs administered to diseased rats and mice.
January 14, 2016
…is delivered during fast ignition experiments and improve energy delivery to the fuel target.
May 20, 2019
Imagine a technology that could target pesticides to treat specific spots deep within the soil, making them more effective at controlling infestations while limiting their toxicity to the environment. Researchers at UC San Diego and Case Western Reserve University have taken a step toward that goal.
February 16, 2017
…Use DNA Origami to Target Cancer A team of engineering students has a cancer-fighting idea up its sleeve—and the sleeve is nanoscale. The idea is based on a new cutting-edge research tool called DNA origami in which scientists literally fold the molecules of life into two- and three-dimensional shapes. The…
October 25, 2019
A new type of micromotor—powered by ultrasound and steered by magnets—can move around individual cells and microscopic particles in crowded environments without damaging them. It can also be controlled to move over 3D obstacles. The work could open up new possibilities for nanomedicine.
