July 16, 2021
…route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain. The findings are published in the July 9, 2021 online issue of Nature Medicine. Figure depicts SARS-CoV-2 spreading through blood vessels (green) to infect pericytes (red), which amplify infection and can spread infection to other cell…
June 23, 2022
…the evolution of the SARS-CoV-2 virus, that is capable of handling the unprecedented amount of genetic data being generated by the quickly evolving pathogen. The software is used to efficiently and accurately track new variants of this virus on what’s known as a phylogenetic tree: a visual history or map…
January 23, 2023
Host-Cell Factors Involved in COVID-19 Infections May Augur Improved Treatments
November 3, 2022
Organoids Reveal How SARS-CoV-2 Damages Brain Cells — and a Potential Treatment
February 24, 2021
…by the pandemic coronavirus SARS-CoV-2, is primarily regarded as a respiratory infection. Yet the virus has also become known for affecting other parts of the body in ways not as well understood, sometimes with longer-term consequences, such as heart arrhythmia, fatigue and “brain fog.” Researchers at University of California San…
March 18, 2021
…Inc., estimate that the SARS-CoV-2 virus was likely circulating undetected for at most two months before the first human cases of COVID-19 were described in Wuhan, China in late-December 2019. Writing in the March 18, 2021 online issue of Science, they also note that their simulations suggest that the mutating…
August 19, 2021
…to pry open the SARS-CoV-2 spike’s receptor binding domain, or RBD (cyan), from a “down” to an "up" position. Credit: Terra Sztain, Surl-Hee Ahn, Lorenzo Casalino (Amaro Lab, UC San Diego). Since the early days of the COVID pandemic, scientists have aggressively pursued the secrets of the mechanisms that allow…
April 28, 2021
…one way in which SARS-CoV-2, the coronavirus that causes COVID-19, hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease. In short, the virus’ genome gets tagged with a special marker by a human enzyme that tells the immune system to stand…
June 9, 2021
…caused by the coronavirus SARS-CoV-2. They wondered how the virus persists on surfaces, particularly in hospitals, and they knew they had only a small window of time to get started if they wanted to capture a snapshot of the “before” situation — before patients with the infection were admitted. After…
September 15, 2020
…researchers have known that SARS-CoV-2, the novel coronavirus that causes COVID-19, primarily uses ACE2 to enter these cells and establish respiratory infections. Finding a way to lock out that interaction between virus and doorknob, as a means to treat the infection, has become the goal of many research studies. University…
